DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling (Q40527099)

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scientific article published on September 2004

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English	DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling	scientific article published on September 2004

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scholarly article

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Europe PubMed Central

21 September 2017

DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling (English)

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Europe PubMed Central

21 September 2017

prostate carcinoma

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based on heuristic

inferred from title

neoplastic invasiveness

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based on heuristic

inferred from title

7

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object named as

David A Jones

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Europe PubMed Central

21 September 2017

author name string

Asmaa Mamoune

1

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Europe PubMed Central

21 September 2017

Jareer Kassis

2

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Europe PubMed Central

21 September 2017

Sourabh Kharait

3

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Europe PubMed Central

21 September 2017

Susanne Kloeker

4

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Europe PubMed Central

21 September 2017

Elisabeth Manos

5

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Europe PubMed Central

21 September 2017

language of work or name

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publication date

1 September 2004

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Europe PubMed Central

21 September 2017

Experimental Cell Research

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Europe PubMed Central

21 September 2017

299

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21 September 2017

91-100

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21 September 2017

1

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21 September 2017

Growth factors and cancer

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.05.008

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Cutting to the chase: calpain proteases in cell motility

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The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

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Dolichol-phosphate-mannose-3 (DPM3)/prostin-1 is a novel phospholipase C-gamma regulated gene negatively associated with prostate tumor invasion

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The plasminogen activation system in tumor growth, invasion, and metastasis

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uPAR: a versatile signalling orchestrator

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Induction of urinary plasminogen activator by retinoic acid results in increased invasiveness of human prostate cancer cells PC-3.

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The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy.

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EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

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Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

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Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor

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The effect of EGFR-related tyrosine kinase activity inhibition on the growth and invasion mechanisms of prostate carcinoma cell lines

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Inhibition of epidermal growth factor-induced invasion by dexamethasone and AP-1 decoy in human squamous cell carcinoma cell lines

1 reference

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Autocrine/paracrine regulation of keratinocyte urokinase plasminogen activator through the TGF-alpha/EGF receptor

1 reference

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Effect of epidermal growth factor on prostate cancer cell line PC3 growth and invasion

1 reference

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Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein

1 reference

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EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells

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7 January 2021

Isolation of a human prostate carcinoma cell line (DU 145)

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7 January 2021

In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals

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7 January 2021

Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

1 reference

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Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

1 reference

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Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

1 reference

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Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase

1 reference

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Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion

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Tumor invasion as dysregulated cell motility

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Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

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Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

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Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

1 reference

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A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility

1 reference

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Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in lamellipodia during EGF-induced motility

1 reference

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Urokinase and the urokinase receptor: association with in vitro invasiveness of human bladder cancer cell lines

1 reference

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Urokinase induces receptor mediated brain tumor cell migration and invasion.

1 reference

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

1 reference

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Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours

1 reference

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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

1 reference

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The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells.

1 reference

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Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling

1 reference

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7 January 2021

1 reference

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Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.

1 reference

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Simultaneous up-regulation of urokinase-type plasminogen activator (uPA) and uPA receptor by hepatocyte growth factor/scatter factor in human glioma cells.

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7 January 2021

Identifiers

10.1016/J.YEXCR.2004.05.008

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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