Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis (Q40503142)

21 September 2017

Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis (English)

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21 September 2017

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Lin Wei

1

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21 September 2017

Yu Yang

series ordinal

2

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21 September 2017

Xin Zhang

series ordinal

3

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21 September 2017

Qiang Yu

series ordinal

4

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21 September 2017

language of work or name

English

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publication date

1 December 2004

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21 September 2017

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21 September 2017

23

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21 September 2017

9052-9061

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21 September 2017

56

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208091

21 September 2017

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Selected glimpses into the activation and function of Src kinase

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Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product

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Activation of pp60c-src protein kinase activity in human colon carcinoma

21 January 2018

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Regulation of c-SRC activity and function by the adapter protein CAS

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Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin

21 January 2018

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Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis

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pp60c-src activation in human colon carcinoma

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Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

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Phosphorylation of a Src kinase at the autophosphorylation site in the absence of Src kinase activity

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

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Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells

21 January 2018

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A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product

21 January 2018

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The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase

21 January 2018

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The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

21 January 2018

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Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins

21 January 2018

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Disruption of epithelial cell-matrix interactions induces apoptosis

21 January 2018

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Suppression of anoikis by v-Src but not by activated c-H-ras in human gallbladder epithelial cells

21 January 2018

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Src activation in malignant and premalignant epithelia of Barrett's esophagus

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Association between the PDGF receptor and members of the src family of tyrosine kinases

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CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.

21 January 2018

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Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

21 January 2018

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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

21 January 2018

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Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro

21 January 2018

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Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src)

21 January 2018

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New roles for Src kinases in control of cell survival and angiogenesis

21 January 2018

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Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway.

21 January 2018

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Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src)

21 January 2018

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Aberrant Elevation of Tyrosine-specific Phosphorylation in Human Gastric Cancer Cells

21 January 2018

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Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

21 January 2018

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c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis

21 January 2018

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Differential pp60c-src activity in well and poorly differentiated human colon carcinomas and cell lines

21 January 2018

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Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis

21 January 2018

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Src activation regulates anoikis in human colon tumor cell lines

21 January 2018

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

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Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

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Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530

21 January 2018

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Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: the intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated

21 January 2018

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7 January 2021

Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

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7 January 2021

c-Src mediates mitogenic signals and associates with cytoskeletal proteins upon vascular endothelial growth factor stimulation in Kaposi's sarcoma cells

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7 January 2021

Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylation

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7 January 2021

Site-specific differences in pp60c-src activity in human colorectal metastases

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208091

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Dimensions Publication ID

21 September 2017

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