Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains. (Q40498926)

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4 January 2020

title

Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains (English)

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4 January 2020

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2

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4 January 2020

Maria Magnusson

5

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4 January 2020

Per-Åke Nygren

6

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author name string

Henning P

1

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4 January 2020

Frykholm K

3

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4 January 2020

Ali A

4

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Granio O

7

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Hong SS

8

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4 January 2020

Boulanger P

9

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Lindholm L

10

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4 January 2020

language of work or name

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1 February 2005

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4 January 2020

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4 January 2020

volume

12

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issue

3

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page(s)

211-224

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302408

4 January 2020

exact match

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cites work

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Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells

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Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

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Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions

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Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished

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Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber

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Genetic modification of adenovirus 5 tropism by a novel class of ligands based on a three-helix bundle scaffold derived from staphylococcal protein A.

21 January 2018

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Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability

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A synthetic IgG-binding domain based on staphylococcal protein A.

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A combinatorial library of an alpha-helical bacterial receptor domain

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Single amino acid substitution in the mouse IgG1 Fc region induces drastic enhancement of the affinity to protein A.

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Clinical experience with CD64-directed immunotherapy. An overview

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Antibody-mediated targeting of an adenovirus vector modified to contain a synthetic immunoglobulin g-binding domain in the capsid

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Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin

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Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors.

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Targeting of adenovirus to human renal cell carcinoma cells

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Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma

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Retargeting to EGFR enhances adenovirus infection efficiency of squamous cell carcinoma

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Endocytosis of adenovirus and adenovirus capsid proteins

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Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein

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Engineering of Fc(1) and Fc(3) from human immunoglobulin G to analyse subclass specificity for staphylococcal protein A.

21 January 2018

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The amino terminus of the adenovirus fiber protein encodes the nuclear localization signal

21 January 2018

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Engineering streptococcal protein G for increased alkaline stability

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Determination of the nucleotide sequence for the penton-base gene of human adenovirus type 5.

21 January 2018

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Update on adenovirus and its vectors

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7 January 2021

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

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Anti-tumor effects of toxins targeted to the prostate specific membrane antigen

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Biological characterization and oncogene expression in human colorectal carcinoma cell lines

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Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

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Adenovirus endocytosis

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302408

1 reference

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Dimensions Publication ID

4 January 2020

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