Steroid 5 alpha-reductase 2 (Q4048886)

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mammalian protein found in Homo sapiens

SRD5A2
type II 5-alpha reductase
SR type 2
Steroid 5-alpha-reductase 2
3-oxo-5-alpha-steroid 4-dehydrogenase 2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
5 alpha-SR2
S5AR 2

Language	Label	Description	Also known as
English	Steroid 5 alpha-reductase 2	mammalian protein found in Homo sapiens	SRD5A2 type II 5-alpha reductase SR type 2 Steroid 5-alpha-reductase 2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 5 alpha-SR2 S5AR 2

Statements

1 reference

13 November 2019

UniProt protein ID

steroid 5-alpha reductase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31213

3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

oxidoreductase activity, acting on the CH-CH group of donors

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

sterol 5-alpha reductase activity

determination method

1 reference

8 April 2019

Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

cholestenone 5-alpha-reductase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

oxidoreductase activity

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

3-oxo-5-alpha-steroid 4-dehydrogenase activity

determination method

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

testosterone dehydrogenase [NAD(P)] activity

determination method

1 reference

8 April 2019

Biochemical and pharmacogenetic dissection of human steroid 5 alpha-reductase type II

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

3-oxo-5-alpha-steroid 4-dehydrogenase activity

determination method

organelle membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

determination method

2 references

cell body fiber

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

intracellular membrane-bounded organelle

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

neuronal cell body

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

endoplasmic reticulum

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

biological process

cell differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

phthalate metabolic process

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

biphenyl metabolic process

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

response to organic cyclic compound

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

lipid metabolism

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

response to testosterone

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

response to steroid hormone

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

cell-cell signaling

determination method

1 reference

8 April 2019

Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

response to peptide hormone

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

sex differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

response to organic substance

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

steroid catabolic process

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

response to nutrient levels

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

dibenzo-p-dioxin metabolic process

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

hypothalamus development

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

bone development

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

hippocampus development

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

response to follicle-stimulating hormone

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

steroid metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

androgen biosynthetic process

determination method

progesterone metabolic process

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

testosterone biosynthetic process

determination method

1 reference

8 April 2019

Biochemical and pharmacogenetic dissection of human steroid 5 alpha-reductase type II

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

steroid biosynthetic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

male genitalia development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

female genitalia development

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31213&geneProductId=UniProtKB:P31213

determination method

androgen metabolic process

determination method

1 reference

8 April 2019

Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

male gonad development

determination method

1 reference

8 April 2019

Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31213

determination method

physically interacts with

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Gene Atlas image

PBB GE SRD5A2 206938 at fs.png
732 × 530; 12 KB

0 references

3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31213

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000477587

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477587

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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