Animal models for disorders of hepatic lipoprotein metabolism. (Q40480072)

20 September 2017

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title

Animal models for disorders of hepatic lipoprotein metabolism. (English)

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20 September 2017

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T E Willnow

1

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PubMed ID

7670924

20 September 2017

J Herz

series ordinal

2

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20 September 2017

1 May 1995

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Journal of Molecular Medicine

20 September 2017

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20 September 2017

73

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20 September 2017

5

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20 September 2017

213-220

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https://scigraph.springernature.com/pub.10.1007/bf00189920

20 September 2017

0 references

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12 December 2020

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein

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12 December 2020

The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330

1 reference

12 December 2020

Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice

1 reference

12 December 2020

Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

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12 December 2020

Correction: LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation

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12 December 2020

The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor

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12 December 2020

Targeted oncogene activation by site-specific recombination in transgenic mice

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12 December 2020

Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects

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12 December 2020

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

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12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

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12 December 2020

Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity

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12 December 2020

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

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12 December 2020

Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor.

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12 December 2020

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

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12 December 2020

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A

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12 December 2020

Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector

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12 December 2020

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor

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12 December 2020

Altering the genome by homologous recombination

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12 December 2020

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

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12 December 2020

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

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12 December 2020

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes

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12 December 2020

Effect of the 39-kDa receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in the rat.

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12 December 2020

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

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12 December 2020

Carbohydrate-Specific Receptors of the Liver

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12 December 2020

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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12 December 2020

Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression

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12 December 2020

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

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12 December 2020

Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo

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12 December 2020

A conjugate between human urokinase and saporin, a type-1 ribosome-inactivating protein, is selectively cytotoxic to urokinase receptor-expressing cells

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12 December 2020

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

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12 December 2020

Nerve regeneration occurs in the absence of apolipoprotein E in mice.

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12 December 2020

Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells

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12 December 2020

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor

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12 December 2020

A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein

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12 December 2020

Animal models of human genetic diseases

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12 December 2020

Tissue- and site-specific DNA recombination in transgenic mice

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12 December 2020

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator

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12 December 2020

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance

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12 December 2020

Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist

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12 December 2020

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

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12 December 2020

Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER.

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12 December 2020

Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice

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12 December 2020

The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein

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12 December 2020

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase

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12 December 2020

gp330 associates with a 44-kDa protein in the rat kidney to form the Heymann nephritis antigenic complex

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12 December 2020

Members of the low density lipoprotein receptor family mediate cell entry of a minor-group common cold virus

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12 December 2020

39-kD protein inhibits tissue-type plasminogen activator clearance in vivo

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12 December 2020

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

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12 December 2020

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

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12 December 2020

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

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12 December 2020

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

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12 December 2020

The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins

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12 December 2020

The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor

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12 December 2020

Analysis of ligand recognition by the purified alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein). Evidence that high affinity of alpha 2-macroglobulin-proteinase complex is achieved by binding to adjacent receptors

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12 December 2020

Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

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12 December 2020

Identifiers

DOI

10.1007/BF00189920

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release_vbynku2f5na5lme22sinjmci2u

20 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vbynku2f5na5lme22sinjmci2u

24 November 2022

mapped directly with Wikidata item

PubMed ID

7670924

1 reference

PubMed ID

7670924