Regulator of G protein signaling 4 (Q4047848)

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mammalian protein found in Homo sapiens

• uniprot:P49798
• regulator of G-protein signaling 4
• RGS4
• schizophrenia disorder 9

edit

Language	Label	Description	Also known as
English	Regulator of G protein signaling 4	mammalian protein found in Homo sapiens	uniprot:P49798 regulator of G-protein signaling 4 RGS4 schizophrenia disorder 9

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49798

part of

RGS domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49798

Regulator of G-protein signalling 4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49798

RGS, subdomain 1/3

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49798

Regulator of G protein signalling

1 reference

based on heuristic

inferred from protein domain or family

Regulator of G-protein signalling 4, RGS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49798

encoded by

RGS4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49798

molecular function

G-protein alpha-subunit binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

calmodulin binding

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

GTPase activator activity

determination method

IBA

IEA

TAS

4 references

retrieved

21 June 2018

stated in

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

TAS

retrieved

21 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

21 June 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IBA

GTPase activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

GTPase activator activity

determination method

IEA

TAS

3 references

retrieved

8 April 2019

stated in

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

cell component

cytoplasm

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

8 April 2019

stated in

Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs

GOA

curator

Community Assessment of Community Annotation with Ontologies

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IDA

cytosol

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

plasma membrane

determination method

IBA

IEA

2 references

retrieved

21 June 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IBA

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

nucleus

determination method

IDA

1 reference

retrieved

27 March 2018

stated in

Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs

GOA

curator

Community Assessment of Community Annotation with Ontologies

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IDA

protein-containing complex

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

nucleus

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

retrieved

8 April 2019

stated in

Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs

GOA

curator

Community Assessment of Community Annotation with Ontologies

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IDA

plasma membrane

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

biological process

positive regulation of GTPase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of signal transduction

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49798

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of G protein-coupled receptor signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

regulation of G protein-coupled receptor signaling pathway

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

G protein-coupled receptor signaling pathway

determination method

IEA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49798&geneProductId=UniProtKB:P49798

determination method

IEA

response to amphetamine

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

brain development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

positive regulation of heart rate

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

response to cocaine

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

response to morphine

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

response to ethanol

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

regulation of calcium ion transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of dopamine receptor signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of cell growth involved in cardiac muscle cell development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

regulation of actin filament organization

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of glycine import across plasma membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

regulation of potassium ion transmembrane transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

negative regulation of potassium ion transmembrane transport

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

dorsal root ganglion development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

positive regulation of excitatory postsynaptic potential

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

G protein-coupled receptor signaling pathway

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49798

determination method

IEA

Gene Atlas image

PBB GE RGS4 204337 at fs.png
732 × 530; 11 KB

0 references

has part(s)

RGS domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49798

Regulator of G-protein signalling 4, RGS domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49798

Identifiers

RefSeq protein ID

NP_001095915

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5999

NP_001106851

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5999

NP_001106852

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5999

NP_005604

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5999

UniProt protein ID

P49798

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49798

Ensembl protein ID

ENSP00000356882

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356882

ENSP00000356884

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356884

ENSP00000356885

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356885

ENSP00000397181

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000397181

ENSP00000433261

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000433261

ENSP00000432194

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000432194

ENSP00000436106

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000436106

Freebase ID

/m/02z61l_

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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