Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system. (Q40457868)

20 September 2017

Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system. (English)

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20 September 2017

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Tobias Anton

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20 September 2017

Sebastian Bultmann

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2

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20 September 2017

Heinrich Leonhardt

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3

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20 September 2017

Yolanda Markaki

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4

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20 September 2017

12 March 2014

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20 September 2017

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20 September 2017

5

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20 September 2017

2

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20 September 2017

163-172

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describes a project that uses

20 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4049922/fullTextXML

inferred from PubMed Central ID database lookup

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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

22 September 2017

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells

22 September 2017

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22 September 2017

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22 September 2017

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Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation

22 September 2017

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

22 September 2017

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Heritable genome editing in C. elegans via a CRISPR-Cas9 system

22 September 2017

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

22 September 2017

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Combined immunofluorescence and DNA FISH on 3D-preserved interphase nuclei to study changes in 3D nuclear organization

22 September 2017

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

22 September 2017

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

22 September 2017

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Efficient genome editing in zebrafish using a CRISPR-Cas system

22 September 2017

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RNA-guided human genome engineering via Cas9

22 September 2017

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Multiplex genome engineering using CRISPR/Cas systems

22 September 2017

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The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity

22 September 2017

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Fluorescence in situ hybridization applications for super-resolution 3D structured illumination microscopy.

22 September 2017

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Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway

22 September 2017

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Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein.

22 September 2017

1 reference

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

22 September 2017

1 reference

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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

22 September 2017

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Assembly of custom TALE-type DNA binding domains by modular cloning

22 September 2017

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Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

22 September 2017

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A TALE nuclease architecture for efficient genome editing

22 September 2017

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A guide to super-resolution fluorescence microscopy

22 September 2017

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The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation

22 September 2017

1 reference

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Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells

22 September 2017

1 reference

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Heterochromatin and the cohesion of sister chromatids

22 September 2017

1 reference

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Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

22 September 2017

1 reference

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Spatial quantitative analysis of fluorescently labeled nuclear structures: problems, methods, pitfalls.

22 September 2017

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CENP-B controls centromere formation depending on the chromatin context

22 September 2017

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22 September 2017

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The human CENP-A centromeric nucleosome-associated complex

22 September 2017

1 reference

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DNA labeling in living cells

22 September 2017

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The role of heterochromatin in centromere function

22 September 2017

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Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes

22 September 2017

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New types of mouse centromeric satellite DNAs

22 September 2017

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Telomeres and telomerase: their mechanisms of action and the effects of altering their functions

22 September 2017

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Senescence and immortalization: role of telomeres and telomerase

22 September 2017

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Mouse centric and pericentric satellite repeats form distinct functional heterochromatin

22 September 2017

1 reference

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Closed chromatin loops at the ends of chromosomes

22 September 2017

1 reference

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Visualizing telomere dynamics in living mammalian cells using PNA probes

22 September 2017

1 reference

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CENP-B Interacts with CENP-C Domains Containing Mif2 Regions Responsible for Centromere Localization

22 September 2017

1 reference

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Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells

22 September 2017

1 reference

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Requirement of heterochromatin for cohesion at centromeres

22 September 2017

1 reference

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Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B.

22 September 2017

1 reference

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Design and selection of novel Cys2His2 zinc finger proteins

22 September 2017

1 reference

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Centromeres: getting a grip of chromosomes

22 September 2017

1 reference

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Design of novel sequence-specific DNA-binding proteins

22 September 2017

1 reference

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Differences in the localization and morphology of chromosomes in the human nucleus.

22 September 2017

1 reference

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Mammalian telomeres end in a large duplex loop

22 September 2017

1 reference

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Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

22 September 2017

1 reference

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In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition

22 September 2017

1 reference

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Analysis of protein-DNA and protein-protein interactions of centromere protein B (CENP-B) and properties of the DNA-CENP-B complex in the cell cycle

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Nucleotide sequence of mouse satellite DNA.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Sequence organization and cytological localization of the minor satellite of mouse

22 September 2017

1 reference

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Identification of a subdomain of CENP-B that is necessary and sufficient for localization to the human centromere

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Centromere protein B assembles human centromeric alpha-satellite DNA at the 17-bp sequence, CENP-B box

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Efficient selection for high-expression transfectants with a novel eukaryotic vector

22 September 2017

1 reference

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Telomere associations in interphase nuclei: possible role in maintenance of interphase chromosome topology

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Mouse centromere mapping using oligonucleotide probes that detect variants of the minor satellite.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

The organization of the mouse satellite DNA at centromeres.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049922

20 August 2018

1 reference

https://api.crossref.org/works/10.4161%2FNUCL.28488

3D-FISH on Cultured Cells Combined with Immunostaining

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24637835

12 December 2020

inferred from PubMed ID database lookup

Live visualization of chromatin dynamics with fluorescent TALEs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24637835

12 December 2020

inferred from PubMed ID database lookup

Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24637835

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/NUCL.28488

1 reference

20 September 2017

1 reference

20 September 2017

1 reference