PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. (Q40456149)

20 September 2017

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. (English)

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20 September 2017

6

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20 September 2017

Takashi Nishimura

1

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20 September 2017

Tomoya Yamaguchi

2

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20 September 2017

Katsuhiro Kato

3

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20 September 2017

Masato Yoshizawa

4

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20 September 2017

Yo-ichi Nabeshima

5

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20 September 2017

Mikio Hoshino

7

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20 September 2017

Kozo Kaibuchi

8

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20 September 2017

20 February 2005

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7

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20 September 2017

270-277

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3

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https://scigraph.springernature.com/pub.10.1038/ncb1227

20 September 2017

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The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity

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PIP3 is involved in neuronal polarization and axon formation.

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Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

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PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

21 January 2018

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The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

21 January 2018

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Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology.

21 January 2018

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Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

21 January 2018

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Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth

21 January 2018

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A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

21 January 2018

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Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

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Regulation of Tiam1-Rac signalling.

21 January 2018

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Baz, Par-6 and aPKC are not required for axon or dendrite specification in Drosophila.

21 January 2018

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Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.

21 January 2018

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Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

21 January 2018

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Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

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Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1

21 January 2018

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CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth

21 January 2018

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21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Evidence for the involvement of Tiam1 in axon formation

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1227

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20 September 2017

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