Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance. (Q40454536)

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scientific article published on April 2010

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English	Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance.	scientific article published on April 2010

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scholarly article

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17 January 2020

Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance (English)

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17 January 2020

multiple drug resistance

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based on heuristic

inferred from title

Pseudomonas aeruginosa

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inferred from title

Cecilia Andresen

1

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17 January 2020

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Lars-Göran Mårtensson

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author name string

Shah Jalal

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Yi Wang

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Anngelica Jarl

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Bo Liedberg

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Bengt Wretlind

8

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Maria Sunnerhagen

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publication date

1 April 2010

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17 January 2020

Protein Science

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680-692

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17 January 2020

4

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17 January 2020

Linking folding and binding

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Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition

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22 September 2017

The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR

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22 September 2017

The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.

1 reference

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Molecular mechanisms of antibacterial multidrug resistance

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Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins.

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Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions.

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Crystal Structure of Enterococcus faecalis SlyA-like Transcriptional Factor

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Structural biology of bacterial multidrug resistance gene regulators

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Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors

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22 September 2017

The mexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: characterization of mutations compromising activity

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22 September 2017

Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa

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Disordered to ordered folding in the regulation of diphtheria toxin repressor activity

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The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution

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Proline in α-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor

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22 September 2017

MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region

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Efflux-mediated resistance to fluoroquinolones in gram-positive bacteria and the mycobacteria

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22 September 2017

In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system MexA-MexB-OprM.

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A self-consistent method for the analysis of protein secondary structure from circular dichroism.

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Analysis of protein circular dichroism spectra for secondary structure using a simple matrix multiplication

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17 June 2018

Transketolase A, an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR.

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20 August 2018

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Negative cooperativity of uric acid binding to the transcriptional regulator HucR from Deinococcus radiodurans

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Bacteriostatic and bactericidal activities of eight fluoroquinolones against MexAB-OprM-overproducing clinical strains of Pseudomonas aeruginosa

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DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra.

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20 August 2018

Contribution of the MexAB-OprM multidrug efflux system to the beta-lactam resistance of penicillin-binding protein and beta-lactamase-derepressed mutants of Pseudomonas aeruginosa.

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Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa.

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20 August 2018

Rapid identification of mutations in a multidrug efflux pump in Pseudomonas aeruginosa

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12 December 2020

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Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding

1 reference

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12 December 2020

based on heuristic

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Molecular mechanism of MexR-mediated regulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Crystal Structure of the Transcriptional Regulator HucR from Deinococcus radiodurans Reveals a Repressor Preconfigured for DNA Binding

1 reference

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12 December 2020

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Two-way interdomain signal transduction in tetracycline repressor

1 reference

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An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus

1 reference

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Mutation in mexR-gene leading to drug resistance in corneal keratitis in human

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20095047

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PRO.343

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17 January 2020

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Europe PubMed Central

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17 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20095047%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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