Free fatty acids increase PGC-1alpha expression in isolated rat islets. (Q40454071)

20 September 2017

Free fatty acids increase PGC-1alpha expression in isolated rat islets. (English)

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20 September 2017

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Peixiang Zhang

1

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20 September 2017

Chang Liu

2

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20 September 2017

Chunni Zhang

3

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20 September 2017

Yan Zhang

4

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20 September 2017

Pingping Shen

5

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20 September 2017

Junfeng Zhang

6

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20 September 2017

Chen-Yu Zhang

7

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20 September 2017

language of work or name

English

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publication date

1 February 2005

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20 September 2017

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20 September 2017

579

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6

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20 September 2017

1446-1452

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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Cloning and mRNA tissue distribution of human PPARgamma coactivator-1.

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Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression

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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

21 January 2018

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Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

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1 reference

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Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a beta(3)-adrenergic agonist and lack of effect of leptin

21 January 2018

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21 January 2018

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Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

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Metabolic coupling factors in pancreatic beta-cell signal transduction

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Mitochondrial function in normal and diabetic beta-cells

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Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

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Experimental models of transcription factor-associated maturity-onset diabetes of the young

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Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice

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Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats

21 January 2018

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

21 January 2018

1 reference

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Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

21 January 2018

1 reference

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Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

21 January 2018

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

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Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

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1 reference

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A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of beta-cell dysfunction in the obese diabetic db/db mouse.

21 January 2018

1 reference

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Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

21 January 2018

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Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

21 January 2018

1 reference

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Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion.

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1 reference

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Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.

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Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives

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Binding of [3H]forskolin to rat brain membranes

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Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets

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The Effect of Fasting on Tissue Cyclic cAMP and Plasma Glucagon in the Obese Hyperglycemic Mouse

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10.1016/J.FEBSLET.2005.01.046

21 January 2018

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20 September 2017

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