Cell-based gene therapy experiments in murine experimental autoimmune encephalomyelitis (Q40445781)

20 September 2017

title

Cell-based gene therapy experiments in murine experimental autoimmune encephalomyelitis (English)

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20 September 2017

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Louie KA

1

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20 September 2017

Weiner LP

2

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20 September 2017

Du J

3

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20 September 2017

Kochounian HH

4

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20 September 2017

Fling SP

5

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20 September 2017

Wei W

6

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20 September 2017

McMillan M

7

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20 September 2017

publication date

1 July 2005

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20 September 2017

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20 September 2017

volume

12

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20 September 2017

issue

14

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20 September 2017

page(s)

1145-1153

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302503

20 September 2017

exact match

0 references

1 reference

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The current status of clinical gene therapy

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Human gene therapy comes of age.

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New concepts in the immunopathogenesis of multiple sclerosis

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Immunological aspects of demyelinating diseases

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Multiple sclerosis: a pivotal role for the T cell in lesion development

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A gender gap in autoimmunity.

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HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course

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HLA typing in the United Kingdom multiple sclerosis genome screen

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HL-A antigens and multiple sclerosis.

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Gene therapy in autoimmune, demyelinating disease of the central nervous system

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The therapeutic use of gene therapy in inflammatory demyelinating diseases of the central nervous system

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Gene therapy in experimental autoimmune encephalomyelitis

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The application of gene therapy in autoimmune diseases

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Treatment of autoimmune disease by adoptive cellular gene therapy

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T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire

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Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

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Minireview: autoimmune responses to myelin proteolipid protein

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Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice

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Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

21 January 2018

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Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

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Epitope spreading in immune-mediated diseases: implications for immunotherapy

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Gene therapy in a murine model for clinical application to multiple sclerosis

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Characterization of a major encephalitogenic T cell epitope in SJL/J mice with synthetic oligopeptides of myelin basic protein

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Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals

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21 January 2018

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Rat KC cDNA cloning and mRNA expression in lung macrophages and fibroblasts

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Long-term erythropoietin gene expression from transduced cells in bioisolator devices

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Disease modifying therapies in multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines

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Immunotherapy of multiple sclerosis: where are we? Where should we go?

21 January 2018

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Immunotherapy of multiple sclerosis: the end of the beginning

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Antigen-induced regulatory T cells in autoimmunity

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Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-beta1.

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Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit

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Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells

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Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.

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Pre-emptive targeting of the epitope spreading cascade with genetically modified regulatory T cells during autoimmune demyelinating disease

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Complete protection from relapsing experimental autoimmune encephalomyelitis induced by syngeneic B cells expressing the autoantigen

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Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases

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An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide

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High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire

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Assessment of animal models for MS and demyelinating disease in the design of rational therapy

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Antigen-based immunotherapy for autoimmune disease: from animal models to humans?

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Antigen-specific immunomodulation via altered peptide ligands

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Specific immunotherapy: one size does not fit all.

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Of mice and not men: differences between mouse and human immunology

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Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis

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Isolation and characterization of autoreactive proteolipid protein-peptide specific T-cell clones from multiple sclerosis patients

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T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects

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Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

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CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis

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Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

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T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

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Genetic basis for clinical expression in multiple sclerosis

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Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis

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The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis

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Quantification of self-recognition in multiple sclerosis by single-cell analysis of cytokine production

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Survival of macroencapsulated allogeneic parathyroid tissue one year after transplantation in nonimmunosuppressed humans.

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The ups and downs of multiple sclerosis therapeutics

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Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway

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Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302503

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Dimensions Publication ID

20 September 2017

1011588987

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1 reference