Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth. (Q40443893)

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9 January 2020

title

Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth (English)

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9 January 2020

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6

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9 January 2020

author name string

Lincoln A Edwards

1

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9 January 2020

B Thiessen

2

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9 January 2020

Wieslawa H Dragowska

3

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9 January 2020

Tim Daynard

4

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9 January 2020

Marcel B Bally

5

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language of work or name

English

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publication date

1 May 2005

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9 January 2020

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9 January 2020

volume

24

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issue

22

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9 January 2020

page(s)

3596-3605

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208427

9 January 2020

exact match

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cites work

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

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Inactivation of Integrin-linked Kinase Induces Aberrant Tau Phosphorylation via Sustained Activation of Glycogen Synthase Kinase 3β in N1E-115 Neuroblastoma Cells

21 January 2018

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 January 2018

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Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

21 January 2018

1 reference

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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

21 January 2018

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Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor

21 January 2018

1 reference

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Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner

21 January 2018

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The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases.

21 January 2018

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Pharmacodynamic behavior of liposomal antisense oligonucleotides targeting Her-2/neu and vascular endothelial growth factor in an ascitic MDA435/LCC6 human breast cancer model.

21 January 2018

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alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

21 January 2018

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7 January 2021

Grading of astrocytomas. A simple and reproducible method.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208427

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208427

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15782140%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 January 2020

0 references

1 reference