GCV phosphates are transferred between HeLa cells despite lack of bystander cytotoxicity (Q40442900)

20 September 2017

title

GCV phosphates are transferred between HeLa cells despite lack of bystander cytotoxicity (English)

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20 September 2017

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B G Gentry

1

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20 September 2017

M Im

2

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20 September 2017

P D Boucher

3

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20 September 2017

R J Ruch

4

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20 September 2017

D S Shewach

5

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20 September 2017

publication date

1 July 2005

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20 September 2017

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20 September 2017

volume

12

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20 September 2017

issue

13

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20 September 2017

page(s)

1033-1041

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302487

20 September 2017

exact match

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Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase

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Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment

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Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy

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Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells

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Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus

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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

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Local inflammation and devascularization--in vivo mechanisms of the "bystander effect" in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma

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Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins

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Stimulation of intercellular communication of poor-communicating cells by gap-junction-competent cells enhances the HSV-TK/GCV bystander effect in vitro

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Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene

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Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes

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Phototoxicity of the fluorescent membrane dyes PKH2 and PKH26 on the human hematopoietic KG1a progenitor cell line

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A non-disruptive technique for loading calcium buffers and indicators into cells

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Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors

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inferred from DOI database lookup

7 January 2021

based on heuristic

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302487

inferred from DOI database lookup

7 January 2021

based on heuristic

Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302487

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302487

1 reference

Dimensions Publication ID

20 September 2017

1021048053

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1 reference