Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition (Q40442177)

20 September 2017

Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition (English)

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20 September 2017

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Antonio Bilancio

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Bart Vanhaesebroeck

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object named as

Bart Vanhaesebroeck

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20 September 2017

Kathrine Abell

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Richard W E Clarkson

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Paul G Tiffen

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Anton I Altaparmakov

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Thomas G Burdon

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Tomoichiro Asano

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Christine J Watson

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27 March 2005

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392-398

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https://scigraph.springernature.com/pub.10.1038/ncb1242

20 September 2017

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cites work

Apoptosis in cancer--implications for therapy

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Apoptosis in mammary gland and cancer

21 January 2018

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Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Stats: transcriptional control and biological impact

21 January 2018

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A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland

21 January 2018

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The STATs of cancer--new molecular targets come of age

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

21 January 2018

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The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

21 January 2018

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Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain

21 January 2018

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A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene

21 January 2018

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Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

21 January 2018

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p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

21 January 2018

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Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

21 January 2018

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Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

21 January 2018

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Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations

21 January 2018

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IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

21 January 2018

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Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

21 January 2018

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

21 January 2018

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Signalling, cell cycle and pluripotency in embryonic stem cells

21 January 2018

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Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha

21 January 2018

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

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STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers

21 January 2018

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Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway

21 January 2018

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Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

21 January 2018

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Computational identification of promoters and first exons in the human genome

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1242

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Dimensions Publication ID

20 September 2017

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