Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux (Q40437437)

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English	Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux	scientific article

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scholarly article

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Europe PubMed Central

20 September 2017

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux (English)

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Europe PubMed Central

20 September 2017

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Robert A. Hegele

5

object named as

Robert A Hegele

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author name string

Carmen A Argmann

1

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Europe PubMed Central

20 September 2017

Jane Y Edwards

2

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Europe PubMed Central

20 September 2017

Cynthia G Sawyez

3

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Europe PubMed Central

20 September 2017

Caroline H O'Neil

4

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Europe PubMed Central

20 September 2017

J Geoffrey Pickering

6

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Europe PubMed Central

20 September 2017

Murray W Huff

7

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Europe PubMed Central

20 September 2017

language of work or name

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publication date

6 April 2005

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Europe PubMed Central

20 September 2017

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

20 September 2017

280

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Europe PubMed Central

20 September 2017

23

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Europe PubMed Central

20 September 2017

22212-22221

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Europe PubMed Central

20 September 2017

Atherosclerosis — An Inflammatory Disease

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https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

A receptor-mediated pathway for cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

The macrophage foam cell as a target for therapeutic intervention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

1 reference

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21 January 2018

Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Prostaglandins and fatty acids regulate transcriptional signaling via the peroxisome proliferator activated receptor nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway

1 reference

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21 January 2018

Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes

1 reference

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21 January 2018

Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

1 reference

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21 January 2018

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

1 reference

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21 January 2018

Structural mechanism for statin inhibition of HMG-CoA reductase

1 reference

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21 January 2018

Nuclear receptor signaling in the control of cholesterol homeostasis: have the orphans found a home?

1 reference

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21 January 2018

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

1 reference

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21 January 2018

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

1 reference

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21 January 2018

Ras and Rho GTPases: a family reunion

1 reference

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21 January 2018

Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking

1 reference

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21 January 2018

Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

1 reference

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21 January 2018

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

1 reference

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21 January 2018

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

ATP-binding cassette transporter A1 and cholesterol trafficking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

1 reference

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21 January 2018

Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins

1 reference

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21 January 2018

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

1 reference

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21 January 2018

Uptake of type III hypertriglyceridemic VLDL by macrophages is enhanced by oxidation, especially after remnant formation

1 reference

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21 January 2018

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1 reference

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21 January 2018

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1 reference

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21 January 2018

Transforming growth factor-beta1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants

1 reference

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21 January 2018

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation

1 reference

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21 January 2018

Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

1 reference

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21 January 2018

Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis

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21 January 2018

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

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21 January 2018

Regulation and functions of Rho-associated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502761200

21 January 2018

Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux

1 reference

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21 January 2018

Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages

1 reference

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21 January 2018

Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).

1 reference

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Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases

1 reference

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21 January 2018

Effect of pitavastatin on apolipoprotein A-I production in HepG2 cell

1 reference

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Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease.

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Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M502761200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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