Backbone modifications in oligonucleotides and peptide nucleic acid systems (Q40428323)

20 September 2017

1 reference

title

Backbone modifications in oligonucleotides and peptide nucleic acid systems (English)

1 reference

20 September 2017

1 reference

4

S. Wendeborn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7583633

24 May 2024

author name string

A. De Mesmaeker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7583633

24 May 2024

K. H. Altmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7583633

24 May 2024

A. Waldner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7583633

24 May 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7583633

24 May 2024

publication date

1 June 1995

1 reference

full work available at URL

20 September 2017

https://api.elsevier.com/content/article/PII:0959440X95800964?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

https://api.elsevier.com/content/article/PII:0959440X95800964?httpAccept=text/plain

24 May 2024

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Current Opinion in Structural Biology

24 May 2024

published in

1 reference

20 September 2017

5

1 reference

20 September 2017

3

1 reference

20 September 2017

343-355

1 reference

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

20 September 2017

1

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus

24 May 2024

2

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Nonionic nucleic acid analogs. Synthesis and characterization of dideoxyribonucleoside methylphosphonates

24 May 2024

3

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Syntheses and properties of adenine and thymine nucleoside alkyl phosphotriesters, the neutral analogs of dinucleoside monophosphates

24 May 2024

5

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Phosphorodithioate DNA as a potential therapeutic drug

24 May 2024

6

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Antisense oligonucleotides: a new therapeutic principle

24 May 2024

7

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Current concepts in antisense drug design

24 May 2024

8

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines

24 May 2024

10

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Evaluation of some properties of a phosphorodithioate oligodeoxyribonucleotide for antisense application

24 May 2024

11

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

24 May 2024

12

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Cellular pharmacology of phosphorothioate homooligodeoxynucleotides in human cells

24 May 2024

17

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Cellular uptake of phosphorothioate oligodeoxynucleotides is negatively affected by cell density in a transformed rat tracheal epithelial cell line: implication for antisense approaches

24 May 2024

18

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Differential distribution of oligodeoxynucleotides in developing organs with epithelial-mesenchymal interactions

24 May 2024

19

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.

24 May 2024

21

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis of phosphorothioate-methylphosphonate oligonucleotide co-polymers

24 May 2024

22

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Phosphorodithioate DNA as a potential therapeutic drug

24 May 2024

23

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages

24 May 2024

24

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Oligonucleoside methylphosphonates as antisense reagents

24 May 2024

25

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis of specific diastereomers of a DNA methylphosphonate heptamer, d(CpCpApApApCpA), and stability of base pairing with the normal DNA octamer d(TPGPTPTPTPGPGPC).

24 May 2024

26

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Use of EDTA derivatization to characterize interactions between oligodeoxyribonucleoside methylphosphonates and nucleic acids

24 May 2024

27

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Effect of ionic strength on the hybridization of oligodeoxynucleotides with reduced charge due to methylphosphonate linkages to unmodified oligodeoxynucleotides containing the complementary sequence

24 May 2024

28

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates

24 May 2024

29

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Biochemical and biological effects of nonionic nucleic acid methylphosphonates

24 May 2024

31

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages

24 May 2024

32

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Selective inhibition of Escherichia coli protein synthesis and growth by nonionic oligonucleotides complementary to the 3′ end of 16S rRNA

24 May 2024

34

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Phosphoramidate analogues of DNA: synthesis and thermal stability of heteroduplexes

24 May 2024

35

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Alkyl phosphotriester modified oligodeoxyribonucleotides. VI. NMR and UV spectroscopic studies of ethyl phosphotriester (Et) modified Rp-Rp and Sp-Sp duplexes, (d[GGAA(Et)TTCC])2.

24 May 2024

38

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5'-phosphorothioate linkage.

24 May 2024

41

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Sequence- and strand-specific cleavage in oligodeoxyribonucleotides and DNA containing 3'-thiothymidine

24 May 2024

42

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis and properties of dithymidine phosphate analogues containing 3'-thiothymidine

24 May 2024

43

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis and properties of oligonucleotides containing aminodeoxythymidine units

24 May 2024

44

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Effect of a single 3'-methylene phosphonate linkage on the conformation of an A-DNA octamer double helix

24 May 2024

47

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2′-OMe RNA and an oligonucleotide containing a single amide backbone modification

24 May 2024

65

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis of a carboxamide linked T*T dimer and its incorporation in oligonucleotides

24 May 2024

66

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

24 May 2024

67

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Synthesis and incorporation of methyleneoxy(methylimino) linked thymidine dimer into antisense oligonucleosides

24 May 2024

68

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Unusual conformation of a 3'-thioformacetal linkage in a DNA duplex

24 May 2024

71

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

24 May 2024

73

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules

24 May 2024

76

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

24 May 2024

77

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Structure-Activity Studies of the Binding of Modified Peptide Nucleic Acids (PNAs) to DNA

24 May 2024

78

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

DNA-like double helix formed by peptide nucleic acid

24 May 2024

80

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.

24 May 2024

81

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Antisense and Antigene Properties of Peptide Nucleic Acids

24 May 2024

82

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Strand-invasion of duplex DNA by peptide nucleic acid oligomers

24 May 2024

83

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA.

24 May 2024

84

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

NMR solution structure of a peptide nucleic acid complexed with RNA

24 May 2024

85

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation

24 May 2024

86

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Single base pair mutation analysis by PNA directed PCR clamping

24 May 2024

87

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Sequence selective double strand DNA cleavage by peptide nucleic acid (PNA) targeting using nuclease S1

24 May 2024

88

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

24 May 2024

89

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

Solid-phase synthesis and hybridization properties of DNA containing sulfide-linked dinucleosides

24 May 2024

91

1 reference

https://api.crossref.org/works/10.1016/0959-440X(95)80096-4

24 May 2024

Identifiers

1 reference

20 September 2017

1 reference