Thrombin active site inhibitors (Q40427614)

20 September 2017

1 reference

title

Thrombin active site inhibitors (English)

1 reference

20 September 2017

J. Das

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7582987

23 May 2024

S. D. Kimball

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7582987

23 May 2024

language of work or name

English

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publication date

1 August 1995

1 reference

full work available at URL

20 September 2017

https://api.elsevier.com/content/article/PII:096808969500104O?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

https://api.elsevier.com/content/article/PII:096808969500104O?httpAccept=text/plain

23 May 2024

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Bioorganic & Medicinal Chemistry

23 May 2024

published in

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20 September 2017

3

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20 September 2017

8

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20 September 2017

999-1007

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20 September 2017

1

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

The molecular basis of blood coagulation

23 May 2024

5

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

The coagulation cascade: initiation, maintenance, and regulation

23 May 2024

6

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Activation of blood coagulation factor XIII

23 May 2024

7

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Natural protein proteinase inhibitors and their interaction with proteinases

23 May 2024

10

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

23 May 2024

12

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Journal of Pharmacology and Experimental Therapeutics

23 May 2024

14

222

166

De Mey

1982

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

23 May 2024

15

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin-cellular interactions

23 May 2024

18

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis

23 May 2024

19

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin stimulates PDGF production and monocyte adhesion through distinct intracellular pathways in human endothelial cells

23 May 2024

20

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin

23 May 2024

21

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin interactions with cultured fibroblasts: relationship to mitogenic stimulation

23 May 2024

23

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Localization of the structural domain responsible for the chemotactic properties of thrombin on polymorphonuclear leukocytes

23 May 2024

24

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin signal transduction mechanisms in human glomerular epithelial cells

23 May 2024

25

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile

23 May 2024

27

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Selective thrombin inhibitors: the next generation of anticoagulants

23 May 2024

32

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Direct thrombin inhibitors in cardiovascular medicine

23 May 2024

36

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

23 May 2024

Oral anticoagulant drugs

37

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Kinetics of the inhibition of thrombin by hirudin.

23 May 2024

44

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Current Opinion in Therapeutic Patents

23 May 2024

47

1

869

Walenga

1991

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Hirudin: clinical potential of a thrombin inhibitor

23 May 2024

48

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Hirudin, heparin, and placebo during deep arterial injury in the pig. The in vivo role of thrombin in platelet-mediated thrombosis

23 May 2024

51

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Hirudin in acute myocardial infarction. Safety report from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial

23 May 2024

52

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIa Investigators

23 May 2024

53

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Safety observations from the pilot phase of the randomized r-Hirudin for Improvement of Thrombolysis (HIT-III) study. A study of the Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte (ALKK)

23 May 2024

54

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Thrombin-specific inhibition by and slow cleavage of hirulog-1

23 May 2024

56

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

The action of thrombin on peptide p-nitroanilide substrates. Substrate selectivity and examination of hydrolysis under different reaction conditions

23 May 2024

58

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

D-PHE-PRO-ARGCH2Cl-A selective affinity label for thrombin

23 May 2024

61

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration in rats

23 May 2024

63

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Benzyloxycarbonyl-D-Phe-Pro-methoxypropylboroglycine: a novel inhibitor of thrombin with high selectivity containing a neutral side chain at the P1 position

23 May 2024

66

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-H

23 May 2024

72

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Highly selective tripeptide thrombin inhibitors

23 May 2024

76

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Active site-directed synthetic thrombin inhibitors: synthesis, in vitro and in vivo activity profile of BMY 44621 and analogs. An examination of the role of the amino group in the D-Phe-Pro-Arg-H series

23 May 2024

77

1 reference

https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Effect of a novel thrombin active-site inhibitor on arterial and venous thrombosis

23 May 2024

78

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Retro-binding tripeptide thrombin active-site inhibitors: discovery, synthesis, and molecular modeling

23 May 2024

104

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

Fibrinolytic compromise by simultaneous administration of site-directed inhibitors of thrombin

23 May 2024

107

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https://api.crossref.org/works/10.1016/0968-0896(95)00104-O

23 May 2024

Identifiers

1 reference

20 September 2017

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