TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. (Q40425001)

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English	TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1.	scientific article

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. (English)

1 reference

Europe PubMed Central

20 September 2017

author name string

Koen Andries

1

1 reference

Europe PubMed Central

20 September 2017

Hilde Azijn

2

1 reference

Europe PubMed Central

20 September 2017

Theo Thielemans

3

1 reference

Europe PubMed Central

20 September 2017

Donald Ludovici

4

1 reference

Europe PubMed Central

20 September 2017

Michael Kukla

5

1 reference

Europe PubMed Central

20 September 2017

Jan Heeres

6

1 reference

Europe PubMed Central

20 September 2017

Paul Janssen

7

1 reference

Europe PubMed Central

20 September 2017

Bart De Corte

8

1 reference

Europe PubMed Central

20 September 2017

Johan Vingerhoets

9

1 reference

Europe PubMed Central

20 September 2017

Rudi Pauwels

10

1 reference

Europe PubMed Central

20 September 2017

Marie-Pierre de Béthune

11

1 reference

Europe PubMed Central

20 September 2017

language of work or name

0 references

publication date

1 December 2004

1 reference

Europe PubMed Central

20 September 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

20 September 2017

48

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Europe PubMed Central

20 September 2017

12

1 reference

Europe PubMed Central

20 September 2017

4680-4686

1 reference

Europe PubMed Central

20 September 2017

Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529207

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Travel and the spread of HIV-1 genetic variants.

1 reference

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22 September 2017

Extent of cross-resistance between agents used to treat human immunodeficiency virus type 1 infection in clinically derived isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529207

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Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues

1 reference

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Increasing prevalence of non-clade B HIV-1 strains in heterosexual men and women, as monitored by analysis of reverse transcriptase and protease sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529207

22 September 2017

Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy

1 reference

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22 September 2017

International perspectives on antiretroviral resistance. Nonnucleoside reverse transcriptase inhibitor resistance

1 reference

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The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy

1 reference

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Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions

1 reference

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Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1

1 reference

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A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs

1 reference

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Human serum alpha 1 acid glycoprotein reduces uptake, intracellular concentration, and antiviral activity of A-80987, an inhibitor of the human immunodeficiency virus type 1 protease.

1 reference

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

1 reference

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Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents

1 reference

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17 June 2018

The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds

1 reference

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An open-label assessment of TMC 125--a new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRTI resistance

1 reference

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A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects

1 reference

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Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure

1 reference

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Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen

1 reference

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20 August 2018

Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues

1 reference

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20 August 2018

Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU).

1 reference

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20 August 2018

Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing.

1 reference

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Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes

1 reference

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Alpha 1-acid glycoprotein levels in AIDS patients before and after short-term treatment with zidovudine (ZDV)

1 reference

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Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 V

1 reference

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Dual-attribute continuous monitoring of cell proliferation/cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15561844

12 December 2020

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Identifiers

10.1128/AAC.48.12.4680-4686.2004

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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