Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth (Q40421611)

20 September 2017

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth (English)

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20 September 2017

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8

Brooke T Mossman

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20 September 2017

Deborah A Altomare

1

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20 September 2017

Huihong You

2

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20 September 2017

Guang-Hui Xiao

3

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20 September 2017

Maria E Ramos-Nino

4

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20 September 2017

Kristine L Skele

5

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20 September 2017

Assunta De Rienzo

6

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20 September 2017

Suresh C Jhanwar

7

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20 September 2017

Agnes B Kane

9

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20 September 2017

Joseph R Testa

10

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20 September 2017

language of work or name

English

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publication date

1 September 2005

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20 September 2017

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20 September 2017

24

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20 September 2017

6080-6089

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20 September 2017

40

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208744

20 September 2017

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cites work

SV40 replication in human mesothelial cells induces HGF/Met receptor activation: a model for viral-related carcinogenesis of human malignant mesothelioma

1 reference

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Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model

21 January 2018

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Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

SV40 and the pathogenesis of mesothelioma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

1 reference

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Hepatocyte growth factor/scatter factor and its receptor c-Met are overexpressed and associated with an increased microvessel density in malignant pleural mesothelioma.

21 January 2018

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Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

21 January 2018

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AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

21 January 2018

1 reference

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7 January 2021

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

7 January 2021

Lost in translation: dysregulation of cap-dependent translation and cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

7 January 2021

The multiple roles of PTEN in tumor suppression

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7 January 2021

Mechanisms of resistance to rapamycins

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7 January 2021

eIF4E--from translation to transformation

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7 January 2021

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

7 January 2021

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

7 January 2021

PTEN signaling pathways in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208744

7 January 2021

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208744

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Dimensions Publication ID

20 September 2017

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