Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. (Q40414678)

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12 January 2020

title

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association (English)

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4

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author name string

David B Young

1

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12 January 2020

Jyoti Jonnalagadda

2

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12 January 2020

Magtouf Gatei

3

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Stephen Meyn

5

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12 January 2020

Kum Kum Khanna

6

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language of work or name

English

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publication date

1 June 2005

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Journal of Biological Chemistry

12 January 2020

published in

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12 January 2020

volume

280

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issue

30

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12 January 2020

page(s)

27587-27594

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ATM, a central controller of cellular responses to DNA damage.

12 January 2020

cites work

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

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Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

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The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

21 January 2018

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ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

21 January 2018

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Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development.

21 January 2018

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Nucleocytoplasmic transport: signals, mechanisms and regulation

21 January 2018

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Transport into and out of the cell nucleus

21 January 2018

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Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

21 January 2018

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The human origin recognition complex protein 1 dissociates from chromatin during S phase in HeLa cells

21 January 2018

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The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

21 January 2018

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Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

21 January 2018

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ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes

21 January 2018

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Cellular responses to ionising radiation of AT heterozygotes: differences between missense and truncating mutation carriers

21 January 2018

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Lack of correlation between ATM protein expression and tumour cell radiosensitivity

21 January 2018

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Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control.

21 January 2018

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ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

1 reference

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Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

21 January 2018

1 reference

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Requirement of the MRN complex for ATM activation by DNA damage

21 January 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 January 2018

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Nuclear retention of ATM at sites of DNA double strand breaks

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M411689200

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12 January 2020

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