Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol (Q40405343)

20 September 2017

Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol (English)

1 reference

20 September 2017

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1 reference

Hui-Ren Zhou

1

1 reference

PubMed ID

15976193

20 September 2017

Zahidul Islam

series ordinal

2

1 reference

PubMed ID

15976193

20 September 2017

James J Pestka

series ordinal

3

1 reference

20 September 2017

23 June 2005

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20 September 2017

Toxicological Sciences

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20 September 2017

87

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20 September 2017

1

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20 September 2017

113-122

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Phosphorylation of HDM2 by Akt.

20 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

MAP kinases in the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Kinases: positive and negative regulators of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Overview: apoptotic signaling pathways in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Non-macrocyclic trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Apoptosis - the p53 network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

p53: 25 years after its discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Relationship of Trichothecene Structure to Cox-2 Induction in the Macrophage: Selective Action of Type B (8-Keto) Trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Apoptosis induction by T-2 toxin: activation of caspase-9, caspase-3, and DFF-40/CAD through cytosolic release of cytochrome c in HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Decision making by p53: life, death and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Mitochondrial regulation of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Induction of apoptosis by 4-acetyl-12,13-epoxyl-9-trichothecene-3,15-diol from Isaria japonica Yasuda through intracellular reactive oxygen species formation and caspase-3 activation in human leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol: toxicology and potential effects on humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Genotoxic and non-genotoxic pathways of p53 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Trichothecenes in the environment: relevance to human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Toxicological features of T-2 toxin and related trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Modulation of IL-1beta, IL-6 and TNF-alpha secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Surviving the kiss of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Aerosolized biologic toxins as agents of warfare and terrorism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI234

1 reference

20 September 2017

1 reference

PubMed ID

15976193