PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet (Q40391278)

20 September 2017

PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet (English)

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20 September 2017

1

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20 September 2017

Nadia Cobo-Vuilleumier

4

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Benoit R Gauthier

11

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Livia López Noriega

object named as

Livia López Noriega

7

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author name string

Esther Fuente-Martín

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20 September 2017

Thierry Brun

3

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20 September 2017

Carmen María Jimenez-Moreno

5

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20 September 2017

Irene G Herrera Gomez

6

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20 September 2017

José Manuel Mellado-Gil

8

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20 September 2017

Alejandro Martin-Montalvo

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20 September 2017

Bernat Soria

10

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20 September 2017

language of work or name

English

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publication date

27 October 2015

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20 September 2017

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20 September 2017

5

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20 September 2017

15672

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Creative Commons Attribution 4.0 International

20 September 2017

start time

27 October 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep15672

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cites work

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Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes

22 September 2017

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22 September 2017

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Subpopulations of GFP-marked mouse pancreatic β-cells differ in size, granularity, and insulin secretion

22 September 2017

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NeuroD1 A45T and PAX4 R121W polymorphisms are associated with plasma glucose level of repaglinide monotherapy in Chinese patients with type 2 diabetes.

22 September 2017

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Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

22 September 2017

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In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice

22 September 2017

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The adult mouse and human pancreas contain rare multipotent stem cells that express insulin

22 September 2017

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Beta-cell growth and regeneration: replication is only part of the story

22 September 2017

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P21cip-overexpression in the mouse beta cells leads to the improved recovery from streptozotocin-induced diabetes

22 September 2017

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Expansion of beta-cell mass in response to pregnancy

22 September 2017

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

22 September 2017

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Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans

22 September 2017

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Adaptive beta-cell proliferation is severely restricted with advanced age.

22 September 2017

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Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus.

22 September 2017

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Perplexing Pax: from puzzle to paradigm.

22 September 2017

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A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease

22 September 2017

1 reference

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The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells

22 September 2017

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Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies

22 September 2017

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Pax6 is required for production and maintenance of progenitor cells in postnatal hippocampal neurogenesis

22 September 2017

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The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets

22 September 2017

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PAX4 gene variations predispose to ketosis-prone diabetes

22 September 2017

1 reference

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

22 September 2017

1 reference

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Expression of dominant negative form of PAX4 in human insulinoma

22 September 2017

1 reference

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Pax7 is required for the specification of myogenic satellite cells

22 September 2017

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The biosociology of pancreatic B cells

22 September 2017

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Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits

22 September 2017

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Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy

25 September 2017

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A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells

25 September 2017

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A novel PAX4 mutation in a Japanese patient with maturity-onset diabetes of the young.

15 June 2018

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Reciprocal modulation of adult beta cell maturity by activin A and follistatin

20 August 2018

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The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.

20 August 2018

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Pax4 paired domain mediates direct protein transduction into mammalian cells.

20 August 2018

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Growth and regeneration of adult beta cells does not involve specialized progenitors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

PAX4 mutations in Thais with maturity onset diabetes of the young

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

Very slow turnover of beta-cells in aged adult mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

DNA sequence motifs conserved in endocrine promoters are essential for Pax4 expression.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

Sialylated form of the neural cell adhesion molecule (NCAM): a new tool for the identification and sorting of beta-cell subpopulations with different functional activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622080

Dominant role of the niche in melanocyte stem-cell fate determination

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP15672

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP15672

Pax4 regulatory elements mediate beta cell specific expression in the pancreas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26503027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Association between A1168C polymorphism in PAX4 gene and type 1 diabetes in Han Chinese]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26503027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

WT1 and Pax2 re-expression is required for epithelial-mesenchymal transition in 5/6 nephrectomized rats and cultured kidney tubular epithelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26503027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP15672

1 reference

20 September 2017

1 reference

20 September 2017

1 reference