Inducible dimerization of RET reveals a specific AKT deregulation in oncogenic signaling (Q40381406)

20 September 2017

Inducible dimerization of RET reveals a specific AKT deregulation in oncogenic signaling (English)

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20 September 2017

Barbara Frêche

1

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20 September 2017

Patricia Guillaumot

2

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20 September 2017

Julie Charmetant

3

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20 September 2017

Ludivine Pelletier

4

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20 September 2017

Celine Luquain

5

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20 September 2017

Dale Christiansen

6

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20 September 2017

Marc Billaud

7

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20 September 2017

Serge N Manié

8

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20 September 2017

language of work or name

English

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publication date

24 August 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

44

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20 September 2017

36584-36591

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The GDNF family: signalling, biological functions and therapeutic value

20 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

RET and neuroendocrine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Lipid rafts and signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

How proteins move lipids and lipids move proteins.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

The state of lipid rafts: from model membranes to cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Lipid rafts: elusive or illusive?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Nanoscale organization of multiple GPI-anchored proteins in living cell membranes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Molecular dynamics and interactions for creation of stimulation-induced stabilized rafts from small unstable steady-state rafts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Spatial and temporal control of signaling through lipid rafts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Lipid rafts and membrane dynamics

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

RET proto-oncogene in the development of human cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Oncogenic activation of RET by two distinct FMTC mutations affecting the tyrosine kinase domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

CD40 signaling in human dendritic cells is initiated within membrane rafts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Expression of the receptor tyrosine kinase Ret on the plasma membrane is dependent on calcium

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Anchorage-dependent cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Membrane compartmentation is required for efficient T cell activation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Caveosomes and endocytosis of lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

The sensitivity of lipid domains to small perturbations demonstrated by the effect of Triton

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

Triton promotes domain formation in lipid raft mixtures

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505707200

New EMBO members' review: actin cytoskeleton regulation through modulation of PI(4,5)P(2) rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

BTK regulates PtdIns-4,5-P2 synthesis: importance for calcium signaling and PI3K activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

The Shp-1 and Shp-2, tyrosine phosphatases, are recruited on cell membrane in two distinct molecular complexes including Ret oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505707200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505707200

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20 September 2017

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