Mammalian gene targeting with designed zinc finger nucleases (Q40371944)

19 September 2017

Mammalian gene targeting with designed zinc finger nucleases (English)

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19 September 2017

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Matthew H Porteus

1

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19 September 2017

19 September 2005

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19 September 2017

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19 September 2017

13

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19 September 2017

438-446

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19 September 2017

2

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Mortality in sickle cell disease. Life expectancy and risk factors for early death.

19 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Survival of children with sickle cell disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Altering the genome by homologous recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Positive genetic selection for gene disruption in mammalian cells by homologous recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Chimeric nucleases stimulate gene targeting in human cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Chimeric restriction enzymes: what is next?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Chimeric restriction endonuclease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

DNA recognition by Cys2His2 zinc finger proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Validated zinc finger protein designs for all 16 GNN DNA triplet targets

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Design and selection of novel Cys2His2 zinc finger proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Custom zinc-finger nucleases for use in human cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Gene conversion tracts from double-strand break repair in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

In vivo selection of MGMT(P140K) lentivirus–transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.003

10.1016/J.YMTHE.2005.08.003

7 January 2021

Identifiers

DOI

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19 September 2017

1 reference

PubMed ID

16169774