Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway. (Q40371751)

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7 January 2020

title

Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway (English)

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7 January 2020

2

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7 January 2020

author name string

Fukuyama T

1

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7 January 2020

Kawakatsu T

3

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7 January 2020

Inagaki M

4

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7 January 2020

Takai Y

5

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7 January 2020

language of work or name

English

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publication date

1 January 2006

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7 January 2020

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7 January 2020

volume

25

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7 January 2020

issue

1

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page(s)

8-19

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209010

7 January 2020

exact match

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cites work

Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors

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Linking Rap to cell adhesion

21 January 2018

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Rap1 signalling: adhering to new models

21 January 2018

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Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42.

21 January 2018

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Junctional complexes in various epithelia

21 January 2018

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Involvement of Nectin-activated Cdc42 Small G Protein in Organization of Adherens and Tight Junctions in Madin-Darby Canine Kidney Cells

21 January 2018

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Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.

21 January 2018

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Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.

21 January 2018

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Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

21 January 2018

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Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

21 January 2018

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Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions.

21 January 2018

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Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts.

21 January 2018

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A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.

21 January 2018

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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

21 January 2018

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Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac.

21 January 2018

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Trans-interactions of nectins induce formation of filopodia and Lamellipodia through the respective activation of Cdc42 and Rac small G proteins

21 January 2018

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Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

21 January 2018

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

21 January 2018

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Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.

21 January 2018

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Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells

21 January 2018

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E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts

21 January 2018

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Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3.

21 January 2018

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Molecular architecture of adherens junctions

21 January 2018

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Cadherin engagement regulates Rho family GTPases

21 January 2018

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Rap1 regulates E-cadherin-mediated cell-cell adhesion

21 January 2018

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Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

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Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation.

21 January 2018

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Biology and pathology of nectins and nectin-like molecules

21 January 2018

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Roles of the intercellular adhesion molecule nectin in intracellular signaling

21 January 2018

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Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein

21 January 2018

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Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

21 January 2018

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Nectin and afadin: novel organizers of intercellular junctions.

21 January 2018

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Multifunctional strands in tight junctions

21 January 2018

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Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.

21 January 2018

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Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion

21 January 2018

1 reference

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Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209010

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209010

Rac Activation upon Cell-Cell Contact Formation Is Dependent on Signaling from the Epidermal Growth Factor Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209010

inferred from DOI database lookup

7 January 2021

based on heuristic

E-cadherin-mediated cell-cell attachment activates Cdc42

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209010

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170364%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 January 2020

0 references

1 reference