Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development (Q40349095)

http://europepmc.org/abstract/PMC/5319916

19 June 2018

title

Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development (English)

1 reference

http://europepmc.org/abstract/PMC/5319916

19 June 2018

0 references

5

1 reference

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11 June 2020

William Ka-Kei Wu

10

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11 June 2020

3

Erik J Tokar

1 reference

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11 June 2020

author name string

Natalie S X Ren

1

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11 June 2020

Ming Ji

2

1 reference

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11 June 2020

Evan L Busch

4

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11 June 2020

DeAsia Lewis

6

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11 June 2020

Xiangchun Li

7

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11 June 2020

Aiwen Jin

8

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11 June 2020

Yanping Zhang

9

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11 June 2020

Weichun Huang

11

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11 June 2020

Leping Li

12

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11 June 2020

David C Fargo

13

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11 June 2020

Temitope O Keku

14

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11 June 2020

Xiaoling Li

16

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11 June 2020

Robert S Sandler

15

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11 June 2020

language of work or name

English

0 references

publication date

2 February 2017

1 reference

http://europepmc.org/abstract/PMC/5319916

19 June 2018

published in

Current Biology

1 reference

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11 June 2020

volume

27

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11 June 2020

issue

4

1 reference

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11 June 2020

page(s)

483-494

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28162896%20AND%20SRC:MED&resulttype=core&format=json

Evaluating markers of epithelial-mesenchymal transition to identify cancer patients at risk for metastatic disease

11 June 2020

cites work

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22 June 2018

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Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions

22 June 2018

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22 June 2018

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Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1α-FXR signaling and alters systemic bile acid homeostasis.

22 June 2018

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The Roles of SIRT1 in Cancer

22 June 2018

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Janus-faced role of SIRT1 in tumorigenesis

22 June 2018

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The NF-κB member p65 controls glutamine metabolism through miR-23a.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5319916

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5319916

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

22 June 2018

1 reference

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Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding

22 June 2018

1 reference

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p53 inhibits mRNA 3' processing through its interaction with the CstF/BARD1 complex

22 June 2018

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Hallmarks of Cancer: The Next Generation

22 June 2018

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Sirtuin 1 in lipid metabolism and obesity

22 June 2018

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SIRT1 contributes to telomere maintenance and augments global homologous recombination

22 June 2018

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Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

22 June 2018

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Glutaminolysis yields a metabolic by-product that stimulates autophagy

22 June 2018

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Ammonia derived from glutaminolysis is a diffusible regulator of autophagy

22 June 2018

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Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation

22 June 2018

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DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

22 June 2018

1 reference

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THE METABOLISM OF TUMORS IN THE BODY

22 June 2018

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MYC-induced cancer cell energy metabolism and therapeutic opportunities

22 June 2018

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A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

22 June 2018

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

22 June 2018

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SIRT1, is it a tumor promoter or tumor suppressor?

22 June 2018

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How does SIRT1 affect metabolism, senescence and cancer?

22 June 2018

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

22 June 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

22 June 2018

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22 June 2018

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22 June 2018

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Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

22 June 2018

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Cancer cell metabolism: Warburg and beyond

22 June 2018

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Sirt1 protects against high-fat diet-induced metabolic damage

22 June 2018

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The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

22 June 2018

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

22 June 2018

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Cancer's molecular sweet tooth and the Warburg effect.

22 June 2018

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

22 June 2018

1 reference

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Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

22 June 2018

1 reference

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p53 mutations in colorectal cancer

22 June 2018

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22 June 2018

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Understanding cancer treatment and outcomes: the Cancer Care Outcomes Research and Surveillance Consortium

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28162896

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CUB.2016.12.047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28162896%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28162896%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference