Site-specific PEGylation of native disulfide bonds in therapeutic proteins. (Q40288550)

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19 January 2020

title

Site-specific PEGylation of native disulfide bonds in therapeutic proteins (English)

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19 January 2020

9

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10

Steve Brocchini

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19 January 2020

5

Elisa Pedone

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19 January 2020

1

Sunil Shaunak

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19 January 2020

author name string

Antony Godwin

2

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19 January 2020

Ji-Won Choi

3

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Sibu Balan

4

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19 January 2020

Damotharan Vijayarangam

6

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Sibylle Heidelberger

7

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Ian Teo

8

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publication date

23 April 2006

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19 January 2020

published in

Nature Chemical Biology

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19 January 2020

volume

2

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issue

6

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page(s)

312-313

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https://scigraph.springernature.com/pub.10.1038/nchembio786

19 January 2020

exact match

0 references

cites work

Disulfide bonds and protein folding.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Replacement of the interchain disulfide bridge-forming amino acids A7 and B7 by glutamate impairs the structure and activity of insulin

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Effect of pegylation on pharmaceuticals

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.

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https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Molecular yardsticks. Synthesis of extended equilibrium transfer alkylating cross-link reagents and their use in the formation of macrocycles

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https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Site-directed chemical modification and cross-linking of a monoclonal antibody using equilibrium transfer alkylating cross-link reagents

1 reference

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7 January 2021

Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Structural and biologic characterization of pegylated recombinant IFN-alpha2b

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Use of peginterferon alfa-2a (40 KD) (Pegasys) for the treatment of hepatitis C.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO786

7 January 2021

Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding

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7 January 2021