Cardiosphere-derived cells reverse heart failure with preserved ejection fraction (HFpEF) in rats by decreasing fibrosis and inflammation (Q40286144)

19 September 2017

Cardiosphere-derived cells reverse heart failure with preserved ejection fraction (HFpEF) in rats by decreasing fibrosis and inflammation (English)

1 reference

Heart failure with preserved ejection fraction

19 September 2017

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1 reference

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1

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4 June 2020

Michael R Zile

8

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4 June 2020

author name string

Geoffrey de Couto

2

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4 June 2020

Eli Simsolo

3

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4 June 2020

Jackelyn Valle

4

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4 June 2020

Baiming Sun

5

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4 June 2020

Weixin Liu

6

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4 June 2020

Eleni Tseliou

7

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4 June 2020

Eduardo Marbán

9

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4 June 2020

publication date

1 January 2016

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JACC. Basic to Translational Science

19 September 2017

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4 June 2020

volume

1

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4 June 2020

issue

1-2

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4 June 2020

page(s)

14-28

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Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles

4 June 2020

cites work

1 reference

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Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction

22 September 2017

1 reference

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Intracoronary delivery of self-assembling heart-derived microtissues (cardiospheres) for prevention of adverse remodeling in a pig model of convalescent myocardial infarction

22 September 2017

1 reference

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Inflammation in HFpEF: Key or circumstantial?

22 September 2017

1 reference

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Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin

22 September 2017

1 reference

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Coronary microvascular rarefaction and myocardial fibrosis in heart failure with preserved ejection fraction

22 September 2017

1 reference

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Murine models of diastolic dysfunction and heart failure with preserved ejection fraction

22 September 2017

1 reference

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Breakthroughs in cell therapy for heart disease: focus on cardiosphere-derived cells

22 September 2017

1 reference

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Exosomes as critical agents of cardiac regeneration triggered by cell therapy.

22 September 2017

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Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy

22 September 2017

1 reference

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Angiogenesis, cardiomyocyte proliferation and anti-fibrotic effects underlie structural preservation post-infarction by intramyocardially-injected cardiospheres

22 September 2017

1 reference

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Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction

22 September 2017

1 reference

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Intracoronary cardiosphere-derived cells after myocardial infarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction)

22 September 2017

1 reference

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Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Heart failure with preserved ejection fraction: emerging drug strategies

22 September 2017

1 reference

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A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

22 September 2017

1 reference

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Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Angiotensin-converting enzyme inhibition promotes coronary angiogenesis in the failing heart of Dahl salt-sensitive hypertensive rats

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Preventing progression of cardiac hypertrophy and development of heart failure by paricalcitol therapy in rats

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment

22 September 2017

1 reference

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Epidemiology and clinical course of heart failure with preserved ejection fraction

22 September 2017

1 reference

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Interleukin 6 mediates myocardial fibrosis, concentric hypertrophy, and diastolic dysfunction in rats

22 September 2017

1 reference

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Microvascular rarefaction: the decline and fall of blood vessels

22 September 2017

1 reference

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Extracellular matrix fibrotic markers in heart failure

22 September 2017

1 reference

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The fuzzy logic of physiological cardiac hypertrophy

22 September 2017

1 reference

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Trends in prevalence and outcome of heart failure with preserved ejection fraction

22 September 2017

1 reference

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Diastolic dysfunction in hypertensive hearts: roles of perivascular inflammation and reactive myocardial fibrosis

22 September 2017

1 reference

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Heart failure with preserved left ventricular systolic function; epidemiology, clinical characteristics, and prognosis

22 September 2017

1 reference

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Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle

22 September 2017

1 reference

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Relation of transmitral flow velocity patterns to left ventricular diastolic function: new insights from a combined hemodynamic and Doppler echocardiographic study.

17 June 2018

1 reference

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Left ventricular strain and transmural distribution of structural remodeling in hypertensive heart disease.

17 June 2018

1 reference

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Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND.

20 August 2018

1 reference

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Longitudinal strain impairment as a marker of the progression of heart failure with preserved ejection fraction in a rat model

20 August 2018

1 reference

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Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?

20 August 2018

1 reference

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Diastolic tissue Doppler indexes correlate with the degree of collagen expression and cross-linking in heart failure and normal ejection fraction.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.

20 August 2018

1 reference

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Left heart failure with a normal ejection fraction: identification of different pathophysiologic mechanisms.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4834906

Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure

20 August 2018

1 reference

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Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats

20 August 2018

1 reference

12 December 2020

Evolving changes in Doppler mitral flow velocity pattern in rats with hypertensive hypertrophy

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12 December 2020

Development of heart failure in chronic hypertensive Dahl rats: focus on heart failure with preserved ejection fraction

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12 December 2020

The many faces of heart failure with preserved ejection fraction

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12 December 2020

Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt-sensitive rats

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12 December 2020

The cardiac microvasculature in hypertension, cardiac hypertrophy and diastolic heart failure

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12 December 2020

Inflammatory cells and myocardial fibrosis: spatial and temporal distribution in renovascular hypertensive rats

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12 December 2020

Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-β signaling

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12 December 2020

Heart failure with preserved ejection fraction: time for a new approach?

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12 December 2020

Time-course changes in left ventricular geometry and function during the development of hypertension in Dahl salt-sensitive rats

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12 December 2020

Markers of Inflammation and Fibrosis Are Related to Cardiovascular Damage in Hypertensive Patients with Metabolic Syndrome

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12 December 2020

Prognosis of heart failure with preserved ejection fraction: a 5 year prospective population-based study

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12 December 2020

Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle

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12 December 2020

10.1016/J.JACBTS.2016.01.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27104217%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27104217%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

27104217

1 reference