Biotransformation and bioactivation of 7, 12-dimethylbenz[a]anthracene (7, 12-DMBA). (Q40258743)

18 September 2017

1 reference

title

Biotransformation and bioactivation of 7, 12-dimethylbenz[a]anthracene (7, 12-DMBA). (English)

1 reference

18 September 2017

DiGiovanni J

1

1 reference

PubMed ID

6775921

18 September 2017

Juchau MR

series ordinal

2

1 reference

PubMed ID

6775921

18 September 2017

language of work or name

English

0 references

publication date

1 January 1980

1 reference

18 September 2017

Drug Metabolism Reviews

1 reference

18 September 2017

11

1 reference

18 September 2017

1

1 reference

18 September 2017

61-101

1 reference

Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.

18 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Selective adrenal necrosis and apoplexy induced by 7, 12-dimethylbenz(a)anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Arene oxides: a new aspect of drug metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Polycyclic K-region arene oxides. Products and kinetics of solvolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz[a]-anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 7,12-DIMETHYLBENZ[α]ANTHRACENE BY RAT-LIVER HOMOGENATES

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Characterization of a photoproduct of 7,12-dimethylbenz[a]anthracene and its effects on chick-embryo cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Sodium periodate, sodium chlorite, and organic hydroperoxides as hydroxylating agents in hepatic microsomal steroid hydroxylation reactions catalyzed by cytochrome P -450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Quantitative aspects of the metabolism of 7, 12-dimethylbenz[a]anthracene by liver homogenates from animals of different age, sex and species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolic pathways of 7,12-dimethylbenz[a]anthracene in hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[a]anthracene and related compounds by rat-liver homogenates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Transannular dioxygenation of 9,10-dimethyl-1,2-benzanthracene by cytochrome P-450 oxygenase of rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Microsome-mediated mutagenicities of the dihydrodiols of 7,12-dimethylbenz[a]anthracene: High mutagenic activity of the 3,4-dihydrodiol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The mechanism of microsomal hydroxylation of 7-methylbenz(a)-anthracene and 7,12-dimethylbenz(a)anthracene by oxygen-18 studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

21 January 2018

Chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Aryl Hydrocarbon (Benzo[A]Pyrene) Hydroxylase: A Mixed-Function Oxygenase in Mouse Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Mouse Epidermal Aryl Hydrocarbon Hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Benzo(a)pyrene metabolism in mouse epidermis. Analysis by high pressure liquid chromatography and DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Effects of 7,8-Benzoflavone on Skin Tumor-Initiating Activities of Various 7- and 12-Substituted Derivatives of 7,12-Dimenthylbenz[a]anthracene in Mice2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Effect of Trichloropropene Oxide on the Ability of Polyaromatic Hydrocarbons and Their “K-Region” Oxides To Initiate Skin Tumors in Mice and To Bind to DNA In Vitro2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolism of polycyclic hydrocarbons by rat-lung preparations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Link between carcinogenicity and hepatic metabolism of 7,12-dimethylbenz(alpha)anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Suppression of 7,12-dimethylbenz(alpha) anthracene-induced breast carcinoma by coumarin in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Studies on the metabolism of 7-methylbenz-[a]anthracene and 7,12-dimethylbenz[a]-anthracene and its hydroxymethyl derivatives in rat liver and adrenal homogenates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The effect of dimethylbenz(a)anthracene on murine hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolism of 7,12,-dimethylbenz(a)anthracene by normal and regenerating rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolism and Cytotoxicity of 7,12-Dimethylbenz[a] anthracene by Hamster, Rat and Rabbit Embryo Cell Cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The metabolism of some aromatic hydrocarbons by mouse embryo cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Products obtained after in vitro reaction of 7,12-dimethylbenz[alpha]anthracene 5,6-oxide with nucleic acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure of 7,12-dimethylbenz(a)anthracene-guanosine adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolic activation of the carcinogen 7,12-dimethylbenz[a]anthracene for DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Photosensitivity of dna-bound 7,12-dimethylbenz(a)-anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Cell and microsome mediated binding of 7, 12-dimethylbenz(a)anthracene to DNA studied by fluorescence spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Evidence for the involvement of a diol-epoxide in the binding of 7,12-dimethylbenz(a)anthracene to DNA in cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Formation of 7,12-dimethylbenz[a]anthracene-DNA adducts in 7,8-benzoflavone-treated hamster embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Differences between products of binding of 7,12-dimethylbenz[a]anthracene to DNA in mouse skin and in a rat liver microsomal system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

High microsome-mediated mutagenicity of the 3,4-dihydrodiol of 7-methylbenz[a]anthracene in S. typhimurium TA 98

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: evidence for bay region activation of carcinogenic polycyclic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

The metabolic activation of 7-methylbenz(a)anthracene: the induction of malignant transformation and mutation in mammalian cells by non-K-region dihydrodiols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Correlation between species life span and capacity to activate 7,12-dimethylbenz(a)anthracene to a form mutagenic to a mammalian cell

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure and activity in chemical carcinogenesis: reactivity and carcinogenicity of 7-bromomethylbenz[alpha]anthracene and 7-bromomethyl-12-methylbenz[alpha]anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure and activity in chemical carcinogenesis. Studies of variously substituted 7-bromomethylbenz(a)anthracenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz(a)anthracene and 7-bromomethyl-12-methylbenz(a)anthracene with mouse skin deoxyribonucleic acid in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz( )anthracene and 7-bromomethyl-12-methylbenz( )anthracene with deoxyribonucleic acid in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Structure-carcinogenic activity relationships in the Benz [a] anthracene series

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Fluorescence spectral studies on the metabolic activation of 3-methylcholanthrene and 7,12-dimethylbenz[a]anthracene in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

High mutagenicity of metabolically activated chrysene 1,2 dihydrodiol: Evidence for bay region activation of chrysene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

8,9-Dihydro-8,9-dihydroxybenz(a)anthracene 10,11-oxide: a new type of polycyclic aromatic hydrocarbon metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Identification of four trans-3,4-dihydrodiol metabolites of 7,12-dimethylbenz[a]anthracene and their in vitro DNA-binding activities upon further metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Embryopathic Effects of 7,12-Dimethylbenz(a)anthracene and its Hydroxymethyl Derivatives in the Sprague–Dawley Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Adrenal Necrosis induced by 7-Hydroxymethyl-12-methylbenz(a)anthracene and its Prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Induction of Adrenal Damage and Cancer with Metabolites of 7,12-Dimethylbenz(a)Anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538008994022

10.3109/03602538008994022

21 January 2018

Identifiers

DOI

1 reference

18 September 2017

1 reference

PubMed ID

6775921