Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population (Q40248155)

18 September 2017

Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population (English)

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18 September 2017

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Bernard M Y Cheung

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18 September 2017

Rong Rong

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18 September 2017

Aimin Xu

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4

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18 September 2017

Grace C N Cheung

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18 September 2017

Karen S L Lam

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6

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18 September 2017

1 August 2006

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18 September 2017

Clinical Endocrinology

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18 September 2017

65

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18 September 2017

198-205

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18 September 2017

2

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Obesity and the regulation of energy balance

18 September 2017

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Anatomy and regulation of the central melanocortin system

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Overexpression of Agrt leads to obesity in transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

A frameshift mutation in human MC4R is associated with a dominant form of obesity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

A frameshift mutation in MC4R associated with dominantly inherited human obesity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Several Mutations in the Melanocortin-4 Receptor Gene Including a Nonsense and a Frameshift Mutation Associated with Dominantly Inherited Obesity in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with early-onset obesity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Identification and characterization of melanocortin-4 receptor gene mutations in morbidly obese finnish children and adults

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

A homozygous null mutation delineates the role of the melanocortin-4 receptor in humans.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early onset obesity.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Prevalence of the metabolic syndrome and overweight among adults in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

The prevalence of diabetes, association with cardiovascular risk factors and implications of diagnostic criteria (ADA 1997 and WHO 1998) in a 1996 community-based population study in Hong Kong Chinese. Hong Kong Cardiovascular Risk Factor Steering C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Molecular screening of the human melanocortin-4 receptor gene: identification of a missense variant showing no association with obesity, plasma glucose, or insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Functional characterization of melanocortin-4 receptor mutations associated with childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Functional analyses of melanocortin-4 receptor mutations identified from patients with binge eating disorder and nonobese or obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

The Search for Human Obesity Genes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Prevalence of Mutations and Functional Analyses of Melanocortin 4 Receptor Variants Identified among 750 Men with Juvenile-Onset Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2265.2006.02573.X

10.1111/J.1365-2265.2006.02573.X

21 January 2018

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DOI

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18 September 2017

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