Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa. (Q40205433)

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2 March 2020

title

Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa (English)

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publication date

17 December 2015

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2 March 2020

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2 March 2020

volume

17

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issue

2

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2 March 2020

page(s)

93-104

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https://scigraph.springernature.com/pub.10.1038/gene.2015.60

2 March 2020

exact match

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Fc-receptors as regulators of immunity.

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Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.

21 January 2018

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Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

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A novel FCGR3A intragenic haplotype is associated with increased FcγRIIIa/CD16a cell surface density and population differences.

21 January 2018

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A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor

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A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus

21 January 2018

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Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

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A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease

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Fc gamma receptor III on human neutrophils. Allelic variants have functionally distinct capacities

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Allelic-dependent expression of an activating Fc receptor on B cells enhances humoral immune responses

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Phenotypic variation in IgG receptors by nonclassical FCGR2C alleles

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FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

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Copy number, linkage disequilibrium and disease association in the FCGR locus

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Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

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Genetic analysis of African populations: human evolution and complex disease

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Meta-analysis confirms a role for deletion in FCGR3B in autoimmune phenotypes

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A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

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Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus

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Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: a common susceptibility gene in the Asian populations.

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Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais.

21 January 2018

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A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling

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FCGR3B gene frequencies and FCGR3 variants in a Chinese population from Zhejiang Province

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Ethnic variation in frequency of an allelic polymorphism of human Fc gamma RIIA determined with allele specific oligonucleotide probes.

21 January 2018

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Frequency of FCGR3B alleles in Thai blood donors

21 January 2018

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Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children

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Allelic polymorphisms in the FcgammaRIIC gene can influence its function on normal human natural killer cells

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Functional and clinical consequences of Fc receptor polymorphic and copy number variants.

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Severe lupus nephritis: racial differences in presentation and outcome

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Ethnic and geographical differences in systemic lupus erythematosus: an overview

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Copy number variation of the activating FCGR2C gene predisposes to idiopathic thrombocytopenic purpura

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Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

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Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1038/GENE.2015.60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673965%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference