Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells (Q40204866)

18 September 2017

Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells (English)

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18 September 2017

Pierre-Olivier Estève

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1

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18 September 2017

Hang Gyeong Chin

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2

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18 September 2017

Sriharsa Pradhan

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3

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18 September 2017

language of work or name

English

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publication date

22 November 2006

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Journal of Biological Chemistry

18 September 2017

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18 September 2017

282

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18 September 2017

4

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18 September 2017

2615-2625

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

The same nuclear proteins bind the proximal CACCC box of the human beta-globin promoter and a similar sequence in the enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Transcription from a TATA-less promoter requires a multisubunit TFIID complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

21 January 2018

CpG islands and genes

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https://api.crossref.org/works/10.1074%2FJBC.M606203200

Sp1 elements protect a CpG island from de novo methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Independent repression of a GC-rich housekeeping gene by Sp1 and MAZ involves the same cis-elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Mammalian DNA (cytosine-5) methyltransferases and their expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Chromatin modifying activity of leukaemia associated fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

De novo CpG island methylation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Epigenetic changes in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Sp1 is required for the early response of alpha2(I) collagen to transforming growth factor-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Inhibition of melanoma tumor growth in vivo by survivin targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Expression of IAP family proteins in myelodysplastic syndromes transforming to overt leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606203200

21 January 2018

Identifiers

DOI

10.1074/JBC.M606203200

1 reference

18 September 2017

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