Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs (Q40200372)

18 September 2017

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title

Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs (English)

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18 September 2017

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Faed EM

1

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PubMed ID

6396057

18 September 2017

language of work or name

English

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publication date

1 January 1984

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18 September 2017

Drug Metabolism Reviews

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18 September 2017

15

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18 September 2017

1213-1249

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18 September 2017

5-6

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The fate of bilirubin-IXα glucuronide in cholestasis and during storage in vitro. Intramolecular rearrangement to positional isomers of glucuronic acid

18 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

A note on the structure and chemistry of glucuronic acid monobenzoate

21 January 2018

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Studies in detoxication: 14. The metabolism of veratraldehyde and veratric acid in the rabbit

21 January 2018

1 reference

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The Fate of Bilirubin-IXα Glucuronides in Cholestatic Bile: Sequential Migration of the 1-Acylaglycone to the 2-, 3- and 4-Positions of Glucuronic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Glucuronic acid conjugates of bilirubin-IXα in normal bile compared with post-obstructive bile. Transformation of the 1-O-acylglucuronide into 2-, 3-, and 4-O-acylglucuronides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Separation of two conjugates of clofibric acid (CPIB) found in the urine of subjects taking clofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

The formation of beta-glucuronidase resistant glucuronides by the intramolecular rearrangement of glucuronic acid conjugates at mild alkaline pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

pH dependent formation of beta-glucuronidase resistant conjugates from the biosynthetic ester glucuronide of isoxepac.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Mass spectrometry of acylated sugars as trimethylsilyl ether derivatives. A way for location of long chain fatty acyl groups

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

β-Glucuronidase-resistant bilirubin glucuronide isomers in cholestatic liver disease — Determination of bilirubin metabolites in serum by means of high-pressure liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Measurement of clofibric acid (CPIB) metabolites in plasma of patients on clofibrate therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Clofibrate disposition in renal failure and acute and chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Biochemical studies of toxic agents. The metabolic formation of 1- and 2-menaphthylmercapturic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Formation of mercapturic acids in rats after the administration of aralkyl esters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Enzymatic formation of glutathione-citryl thioester by a mitochondrial system and its inhibition by (-)erythrofluorocitrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases

21 January 2018

1 reference

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Carcinogenicity of lactones. III. The reactions of unsaturated .gamma.-lactones with L-cysteine

21 January 2018

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5-(Tetradecyloxy)-2-furancarboxylic acid and related hypolipidemic fatty acid-like alkyloxyarylcarboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Xenobiotic triglyceride formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Xenobiotic cholesteryl ester formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Nonenzymic protein modification: a general phenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

21 January 2018

The vertebrate eye lens

1 reference

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FURTHER STUDIES ON THE CARCINOGENIC ACTION OF CERTAIN LACTONES AND RELATED SUBSTANCES IN THE RAT AND MOUSE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Investigation of the mechanism of the metabolic activation of chloramphenicol by rat liver microsomes. Identification of a new metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Oxidative metabolism of halothane in the production of altered hepatocyte membrane antigens in acute halothane-induced hepatic necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Halothans hepatitis: allergy or idiosyncrasy?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Acetylation of prostaglandin synthase by aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Distribution of the acetyl compared with the salicyl moiety of acetylsalicylic acid. Acetylation of macromolecules in organs wherein side-effects are manifest.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Risk factors for the development of cholelithiasis in man (second of two parts).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its toxicological significance to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

The chemical estimation of acyl glucuronides and its application to studies on the metabolism of benzoate and salicylate in man.

21 January 2018

1 reference

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Urinary excretion of probenecid and its metabolites in humans as a function of dose

21 January 2018

1 reference

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Biotransformation of Diclofenac Sodium (Voltaren®) in Animals and in Man.: II. Quantitative determination of the unchanged drug and principal phenolic metabolites, in urine and bile

21 January 2018

1 reference

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Failure of alkaline diuresis to enhance diflunisal elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Biotransformation of diclofenac sodium (Voltaren) in animals and in man. I. Isolation and identification of principal metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

The binding of drugs to plasma proteins from patients with poor renal function

21 January 2018

1 reference

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Uricosuric properties of diflunisal in man

21 January 2018

1 reference

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Persistence of antibiotics in blood of patients with acute renal failure. III. Penicillin, streptomycin, erythromycin and kanamycin

21 January 2018

1 reference

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Plasma half-life of clofibric acid in renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Biotransformation and excretion of lorazepam in patients with chronic renal failure

21 January 2018

1 reference

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Propranolol disposition in renal failure

21 January 2018

1 reference

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Propranolol glucuronide cumulation during long-term propranolol therapy: a proposed storage mechanism for propranolol

21 January 2018

1 reference

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Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Decreased clearance of diflunisal in renal insufficiency--an alternative explanation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Effects of probenecid on ketoprofen kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Studies in detoxication. 52. The apparent dissociation constants of some glucuronides, mercapturic acids and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

RENAL TUBULAR MECHANISMS FOR EXCRETION OF ORGANIC ACIDS AND BASES.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538409033562

Salicylate and salicyl conjugates: fluorimetric estimation, biosynthesis and renal excretion in man.

21 January 2018

1 reference

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Conjugation reactions in foreign-compound metabolism: definition, consequences, and species variations

21 January 2018

1 reference

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Micro-analytic detection and structure elucidation of ester-glycosides

21 January 2018

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Chemical Nature of the Catalytic Sites in Glyceraldehyde-3-Phosphate Dehydrogenase

21 January 2018

1 reference

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10.3109/03602538409033562

21 January 2018

Identifiers

DOI

1 reference

18 September 2017

1 reference

PubMed ID

6396057