Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. (Q40195204)

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23 December 2019

title

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia (English)

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23 December 2019

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13

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23 December 2019

14

Iannis Aifantis

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23 December 2019

author name string

Tomas Vilimas

1

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23 December 2019

Joaquina Mascarenhas

2

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23 December 2019

Teresa Palomero

3

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23 December 2019

Malay Mandal

4

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23 December 2019

Silvia Buonamici

5

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23 December 2019

Fanyong Meng

6

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23 December 2019

Benjamín Thompson

7

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23 December 2019

Christina Spaulding

8

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23 December 2019

Sami Macaroun

9

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23 December 2019

Maria-Luisa Alegre

10

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23 December 2019

Barbara L Kee

11

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23 December 2019

Adolfo Ferrando

12

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23 December 2019

language of work or name

English

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publication date

17 December 2006

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23 December 2019

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23 December 2019

volume

13

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23 December 2019

issue

1

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23 December 2019

page(s)

70-77

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https://scigraph.springernature.com/pub.10.1038/nm1524

23 December 2019

exact match

0 references

cites work

NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

Nuclear factor-kappaB in cancer development and progression

21 January 2018

1 reference

The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors

21 January 2018

1 reference

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

1 reference

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

21 January 2018

1 reference

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

21 January 2018

1 reference

Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.

21 January 2018

1 reference

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

21 January 2018

1 reference

21 January 2018

1 reference

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

Commitment to the B lymphoid lineage occurs before DH-JH recombination

21 January 2018

1 reference

Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis

21 January 2018

1 reference

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

Activating Notch1 mutations in mouse models of T-ALL.

21 January 2018

1 reference

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

1 reference

Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

21 January 2018

1 reference

Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions

21 January 2018

1 reference

Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

21 January 2018

1 reference

Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes

21 January 2018

1 reference

Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

21 January 2018

1 reference

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

21 January 2018

1 reference

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors

21 January 2018

1 reference

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

21 January 2018

1 reference

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B

21 January 2018

1 reference

Proteasome inhibitor therapy in multiple myeloma

21 January 2018

1 reference

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

21 January 2018

1 reference

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 January 2018

1 reference

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

21 January 2018

1 reference

Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain

21 January 2018

1 reference

IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways

21 January 2018

1 reference

Basal Expression of IκBα Is Controlled by the Mammalian Transcriptional Repressor RBP-J (CBF1) and Its Activator Notch1

21 January 2018

1 reference

Notch1 augments NF-kappaB activity by facilitating its nuclear retention

21 January 2018

1 reference

Deregulated NOTCH signaling in acute T-cell lymphoblastic leukemia/lymphoma: new insights, questions, and opportunities

21 January 2018

1 reference

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

21 January 2018

1 reference

Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling

21 January 2018

1 reference

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

21 January 2018

1 reference

Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development

21 January 2018

1 reference

Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus

21 January 2018

1 reference

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

21 January 2018

1 reference

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

1 reference

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1524

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17173050%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

1 reference