Downregulation of Bid is associated with PKCepsilon-mediated TRAIL resistance (Q40191065)

18 September 2017

Downregulation of Bid is associated with PKCepsilon-mediated TRAIL resistance (English)

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18 September 2017

Sivaprasad U

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18 September 2017

Shankar E

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2

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18 September 2017

Basu A

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3

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18 September 2017

language of work or name

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22 December 2006

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Cell Death & Differentiation

18 September 2017

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18 September 2017

14

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18 September 2017

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18 September 2017

851-860

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402077

18 September 2017

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cites work

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

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Two CD95 (APO-1/Fas) signaling pathways

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.

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PKCdelta-mediated regulation of FLIP expression in human colon cancer cells

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Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers

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Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells

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Variable expression of protein kinase C epsilon in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis

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Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling

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PKCepsilon controls protection against TRAIL in erythroid progenitors.

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells

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TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway

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Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells

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Involvement of protein kinase C-delta in DNA damage-induced apoptosis

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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BID: a novel BH3 domain-only death agonist

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7 January 2021

Stimulation of the mitogen-activated protein kinase pathway antagonizes TRAIL-induced apoptosis downstream of BID cleavage in human breast cancer MCF-7 cells

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Involvement of protein kinase C-delta in DNA damage-induced apoptosis.

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Oncogenic transformation alters cisplatin-induced apoptosis in rat embryo fibroblasts

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Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402077

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Dimensions Publication ID

18 September 2017

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