NOD2 contributes to the inflammatory responses of primary murine microglia and astrocytes to Staphylococcus aureus (Q40184178)

18 September 2017

NOD2 contributes to the inflammatory responses of primary murine microglia and astrocytes to Staphylococcus aureus (English)

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18 September 2017

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Staphylococcus aureus

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3

Ian Marriott

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18 September 2017

Xinjie Liu

1

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18 September 2017

Vinita S Chauhan

series ordinal

2

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18 September 2017

language of work or name

English

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publication date

11 March 2010

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18 September 2017

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18 September 2017

474

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2

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93-98

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describes a project that uses

18 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2859426/fullTextXML

inferred from PubMed Central ID database lookup

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NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens

22 September 2017

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Neurogenic exacerbation of microglial and astrocyte responses to Neisseria meningitidis and Borrelia burgdorferi

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Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling

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Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns

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Signalling pathways and molecular interactions of NOD1 and NOD2

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Murine glia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi or Neisseria meningitidis

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Recognition of Staphylococcus aureus-derived peptidoglycan (PGN) but not intact bacteria is mediated by CD14 in microglia

22 September 2017

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Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia

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Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

22 September 2017

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Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

22 September 2017

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

22 September 2017

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

22 September 2017

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Immune function of astrocytes

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22 September 2017

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Neurotoxicity of glia activated by gram-positive bacterial products depends on nitric oxide production

22 September 2017

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Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus

22 September 2017

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Borrelia burgdorferi induces inflammatory mediator production by murine microglia

22 September 2017

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TLR2 mediates neuroinflammation and neuronal damage.

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Functional expression of NOD2, a novel pattern recognition receptor for bacterial motifs, in primary murine astrocytes

20 August 2018

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An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance.

20 August 2018

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Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia

20 August 2018

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Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.

20 August 2018

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Cultured astrocytes express toll-like receptors for bacterial products.

20 August 2018

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Broad expression of Toll-like receptors in the human central nervous system

20 August 2018

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20 August 2018

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Microglial activation by components of gram-positive and -negative bacteria: distinct and common routes to the induction of ion channels and cytokines.

20 August 2018

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Characterization of nucleotide-binding oligomerization domain (NOD) protein expression in primary murine microglia

20 August 2018

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12 December 2020

Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide

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12 December 2020

Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression

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12 December 2020

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12 December 2020

Differential activation of astrocytes by innate and adaptive immune stimuli

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Pneumococcal cell wall components induce nitric oxide synthase and TNF-alpha in astroglial-enriched cultures

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10.1016/J.NEULET.2010.03.013

Identifiers

DOI

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18 September 2017

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18 September 2017

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