Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels (Q40177451)

18 September 2017

Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels (English)

1 reference

18 September 2017

Hans Blokzijl

1

1 reference

18 September 2017

Sara Vander Borght

2

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18 September 2017

Lisette I H Bok

3

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18 September 2017

Louis Libbrecht

4

1 reference

18 September 2017

Mariska Geuken

5

1 reference

18 September 2017

Fiona A J van den Heuvel

6

1 reference

18 September 2017

Gerard Dijkstra

7

1 reference

18 September 2017

Tania A D Roskams

8

1 reference

18 September 2017

Han Moshage

9

1 reference

18 September 2017

Peter L M Jansen

10

1 reference

18 September 2017

Klaas Nico Faber

11

1 reference

18 September 2017

1 June 2007

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Inflammatory Bowel Diseases

18 September 2017

1 reference

18 September 2017

13

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18 September 2017

6

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18 September 2017

710-720

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Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

18 September 2017

1 reference

Mammalian ABC transporters in health and disease

21 January 2018

1 reference

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?

21 January 2018

1 reference

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

21 January 2018

1 reference

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.

21 January 2018

1 reference

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

1 reference

Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes.

21 January 2018

1 reference

The C3435T MDR1 gene polymorphism is not associated with susceptibility for ulcerative colitis in Greek population

21 January 2018

1 reference

Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene

21 January 2018

1 reference

The mdr1a-/- mouse model of spontaneous colitis: a relevant and appropriate animal model to study inflammatory bowel disease

21 January 2018

1 reference

Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver

21 January 2018

1 reference

Induction of Mdr1b expression by tumor necrosis factor-alpha in rat liver cells is independent of p53 but requires NF-kappaB signaling.

21 January 2018

1 reference

Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation.

21 January 2018

1 reference

Inflammation and interleukin-6 mediate reductions in the hepatic expression and transcription of the mdr1a and mdr1b Genes.

21 January 2018

1 reference

Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

21 January 2018

1 reference

Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice.

21 January 2018

1 reference

Suppression of drug-metabolizing enzymes and efflux transporters in the intestine of endotoxin-treated rats

21 January 2018

1 reference

Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells

21 January 2018

1 reference

Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump

21 January 2018

1 reference

High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease.

21 January 2018

1 reference

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

1 reference

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

21 January 2018

1 reference

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

21 January 2018

1 reference

MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes

21 January 2018

1 reference

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

1 reference

A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

21 January 2018

1 reference

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.

21 January 2018

1 reference

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

21 January 2018

1 reference

Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.

21 January 2018

1 reference

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

21 January 2018

1 reference

The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease

21 January 2018

1 reference

Glucocorticoid resistance in inflammatory bowel disease

21 January 2018

1 reference

Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators

21 January 2018

1 reference

Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IBD.20088

1 reference

18 September 2017

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