XEN-D0501, a Novel TRPV1 Antagonist, Does Not Reduce Cough in Refractory Cough Patients. (Q40158261)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

title

XEN-D0501, a Novel Transient Receptor Potential Vanilloid 1 Antagonist, Does Not Reduce Cough in Patients with Refractory Cough (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Mark A Birrell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Michael A Wortley

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Imran Satia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Kimberley Holt

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Jaclyn A. Smith

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

9

Lorcan McGarvey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Sarah A Maher

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Huda Badri

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Patrick Round

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

John Ford

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

language of work or name

English

0 references

publication date

1 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Respiratory and Critical Care Medicine

23 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

volume

196

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

1255-1263

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

Cough in the community: a cross sectional survey and the relationship to gastrointestinal symptoms

23 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Clinical features of the urge-to-cough in patients with chronic cough

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Are there clinical features of a sensitized cough reflex?

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Neurophenotypes in Airway Diseases. Insights from Translational Cough Studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Targeting TRP channels for chronic cough: from bench to bedside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

A capsaicin-receptor homologue with a high threshold for noxious heat

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Capsazepine as a selective antagonist of capsaicin-induced activation of C-fibres in guinea-pig bronchi

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Cough induced by stimulation of capsaicin-sensitive sensory neurons in conscious guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Tiotropium modulates transient receptor potential V1 (TRPV1) in airway sensory nerves: A beneficial off-target effect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Recommendations for the management of cough in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ)

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

TRPA1 agonists evoke coughing in guinea pig and human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Systematic review of randomised controlled trials of over the counter cough medicines for acute cough in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Capsaicin induced cough in cryptogenic fibrosing alveolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Cough and glottic-stop reflex sensitivity in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201704-0769OC

10.1164/RCCM.201704-0769OC

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28650204%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference