Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol. (Q40148056)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26158910%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol (English)

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19 February 2020

main subject

Orthoebolavirus zairense

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transmembrane protein

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2

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19 February 2020

Carmen Ruiz De Almodovar

5

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19 February 2020

author name string

Moritz Hacke

1

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19 February 2020

Andrea Hellwig

3

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19 February 2020

Patricia Himmels

4

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19 February 2020

Britta Brügger

6

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19 February 2020

Felix Wieland

7

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19 February 2020

Andreas M Ernst

8

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19 February 2020

language of work or name

English

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publication date

9 July 2015

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19 February 2020

published in

Nature Communications

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19 February 2020

volume

6

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19 February 2020

page(s)

7688

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https://scigraph.springernature.com/pub.10.1038/ncomms8688

19 February 2020

exact match

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cites work

World struggles to stop Ebola

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Emergence of Zaire Ebola Virus Disease in Guinea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

A practical treatment for patients with Ebola virus disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

21 January 2018

Ebola haemorrhagic fever

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Requirements for cell rounding and surface protein down-regulation by Ebola virus glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Filovirus entry: a novelty in the viral fusion world

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Ebolavirus glycoprotein GP masks both its own epitopes and the presence of cellular surface proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Filovirus assembly and budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The multiple roles of sGP in Ebola pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Shed GP of Ebola virus triggers immune activation and increased vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Downregulation of beta1 integrins by Ebola virus glycoprotein: implication for virus entry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The Ebola virus glycoprotein and HIV-1 Vpu employ different strategies to counteract the antiviral factor tetherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Ebola virus glycoprotein: proteolytic processing, acylation, cell tropism, and detection of neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Biosynthesis and role of filoviral glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Differential induction of cellular detachment by envelope glycoproteins of Marburg and Ebola (Zaire) viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Oligomerization and polymerization of the filovirus matrix protein VP40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Vesicular release of ebola virus matrix protein VP40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Contribution of ebola virus glycoprotein, nucleoprotein, and VP24 to budding of VP40 virus-like particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The GxxxG motif: a framework for transmembrane helix-helix association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Differential Cholesterol Binding by Class II Fusion Proteins Determines Membrane Fusion Properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Stiffened lipid platforms at molecular force foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Discovery of an ebolavirus-like filovirus in europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

On the etiology of an unknown human infection originating from monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The role of lipid rafts in T cell antigen receptor (TCR) signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Lipid cell biology. Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Post-exposure therapy of filovirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Treatment of ebola virus disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Pre-symptomatic diagnosis and treatment of filovirus diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

The Ebola virus matrix protein penetrates into the plasma membrane: a key step in viral protein 40 (VP40) oligomerization and viral egress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Update on activities at the Universal Protein Resource (UniProt) in 2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

CD-HIT Suite: a web server for clustering and comparing biological sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Molecular code for transmembrane-helix recognition by the Sec61 translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Disposition of amphiphilic helices in heteropolar environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS8688

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

21 January 2018

1 reference

12 December 2020

Labeling of cholesterol with filipin in cellular membranes of parenchymatous organs. Standardization of incubation conditions

1 reference

12 December 2020

Biochemical analysis of the secreted and virion glycoproteins of Ebola virus

1 reference

12 December 2020

Enzymac characterization and lipid composition of rat liver subcellular membranes

1 reference

12 December 2020