The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines (Q40110811)

17 September 2017

title

The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines (English)

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17 September 2017

9

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17 September 2017

Kai Uwe Chow

1

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17 September 2017

Daniel Nowak

2

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17 September 2017

Bettina Trepohl

3

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17 September 2017

Simone Hochmuth

4

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17 September 2017

Bernd Schneider

5

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17 September 2017

Dieter Hoelzer

6

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17 September 2017

Paris S Mitrou

7

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17 September 2017

Lothar Bergmann

8

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17 September 2017

Simone Boehrer

10

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17 September 2017

publication date

1 July 2007

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17 September 2017

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17 September 2017

volume

48

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17 September 2017

issue

7

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17 September 2017

page(s)

1379-1388

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AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells

17 September 2017

cites work

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https://api.crossref.org/works/10.1080%2F10428190701385181

Imatinib induces apoptosis in CLL lymphocytes with high expression of Par-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase acti

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

c-MYC: more than just a matter of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

c-Myc target genes involved in cell growth, apoptosis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

CD45: direct and indirect government of immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

TCR signaling: another Abl-bodied kinase joins the cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

Cyclin E and cyclin A are likely targets of Src for PDGF-induced DNA synthesis in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

The mechanism of cell cycle regulation by v-Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

RACK1 regulates G1/S progression by suppressing Src kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701385181

10.1080/10428190701385181

21 January 2018

Identifiers

DOI

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release_yshpiefunrhwhcc7zvvpqrm7ke

17 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/yshpiefunrhwhcc7zvvpqrm7ke

mapped directly with Wikidata item

24 November 2022

based on heuristic

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