Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors. (Q40105848)

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2 January 2020

title

Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors (English)

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6

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author name string

Dent CL

1

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2 January 2020

Lau G

2

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Drake EA

3

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Yoon A

4

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Case CC

5

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publication date

19 July 2007

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2 January 2020

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2 January 2020

volume

14

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issue

18

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2 January 2020

page(s)

1362-1369

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302985

2 January 2020

exact match

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cites work

Drug discovery with engineered zinc-finger proteins

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7 January 2021

Recent developments in the engineering of zinc finger proteins

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Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities

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Development of pro-angiogenic engineered transcription factors for the treatment of cardiovascular disease

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Towards therapeutic applications of engineered zinc finger proteins

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Designer zinc-finger proteins and their applications

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Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

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Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors

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Engineered zinc finger proteins for controlling stem cell fate

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Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.

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Induction of angiogenesis in a mouse model using engineered transcription factors

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An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice.

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An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia.

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Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy.

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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A regulatory system for target gene expression.

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Ecdysone-controlled expression of transgenes

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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Regulation of endogenous gene expression with a small-molecule dimerizer

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7 January 2021

Chemically regulated zinc finger transcription factors

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7 January 2021

A regulatory system for use in gene transfer

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7 January 2021

Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator

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7 January 2021

Ligand-inducible transgene regulation for gene therapy

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The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

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Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

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Ligand-dependent regulation of plasmid-based transgene expression in vivo

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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

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The antiprogestin-dependent GeneSwitch system for regulated gene therapy

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7 January 2021

Antiprogestin-controllable transgene regulation in vivo

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7 January 2021

Importance of the regulation of nuclear receptor degradation

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7 January 2021

Drug inducible transgene expression in brain using a herpes simplex virus vector

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7 January 2021

Ligand-inducible and liver-specific target gene expression in transgenic mice

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7 January 2021

A conditional tissue-specific transgene expression system using inducible GAL4.

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7 January 2021

Regulatable gene expression systems for gene therapy applications: progress and future challenges

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7 January 2021

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

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7 January 2021

Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

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7 January 2021

Negative effect of the transcriptional activator GAL4

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302985

7 January 2021

Regulation of transcriptional activation domain function by ubiquitin

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7 January 2021

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

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7 January 2021

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17637799%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 January 2020

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