Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration (Q40101953)

17 September 2017

Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration (English)

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17 September 2017

Jin-Peng Sun

1

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17 September 2017

Yong Luo

2

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17 September 2017

Xiao Yu

3

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17 September 2017

Wei-Qing Wang

4

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17 September 2017

Bo Zhou

5

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17 September 2017

Fubo Liang

6

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17 September 2017

Zhong-Yin Zhang

7

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17 September 2017

language of work or name

English

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publication date

26 July 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

39

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17 September 2017

29043-29051

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Combinatorial control of the specificity of protein tyrosine phosphatases

17 September 2017

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Protein tyrosine phosphatases in the human genome

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Protein tyrosine phosphatases: prospects for therapeutics

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Genetic analysis of the kinome and phosphatome in cancer

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PRL-1, a unique nuclear protein tyrosine phosphatase, affects cell growth

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Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases

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Mouse PRL-2 and PRL-3, two potentially prenylated protein tyrosine phosphatases homologous to PRL-1

21 January 2018

1 reference

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PRL phosphatases as potential molecular targets in cancer

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Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosome

21 January 2018

1 reference

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The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis

21 January 2018

1 reference

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Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases

21 January 2018

1 reference

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Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling

21 January 2018

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Analysis of stromal-epithelial interactions in prostate cancer identifies PTPCAAX2 as a potential oncogene

21 January 2018

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PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation

21 January 2018

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A phosphatase associated with metastasis of colorectal cancer

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PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility

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PRL-1 tyrosine phosphatase regulates c-Src levels, adherence, and invasion in human lung cancer cells

21 January 2018

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Structural insights into molecular function of the metastasis-associated phosphatase PRL-3

21 January 2018

1 reference

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Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion

21 January 2018

1 reference

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Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms

21 January 2018

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

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Kinetic and mechanistic studies of a cell cycle protein phosphatase Cdc14.

21 January 2018

1 reference

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Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function

21 January 2018

1 reference

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High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases

21 January 2018

1 reference

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Mechanistic studies on protein tyrosine phosphatases

21 January 2018

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Heterotrimer formation, together with isoprenylation, is required for plasma membrane targeting of Gbetagamma.

21 January 2018

1 reference

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Dimerization as a regulatory mechanism in signal transduction

21 January 2018

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

21 January 2018

1 reference

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Kinetic study of the hydrolysis of lecithin monolayers by Crotalus adamanteus .alpha.-phospholipase A2. Monomer-Dimer equilibrium

21 January 2018

1 reference

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Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer

21 January 2018

1 reference

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

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Electrostatic interaction of myristoylated proteins with membranes: simple physics, complicated biology

21 January 2018

1 reference

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

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A polybasic motif allows N-WASP to act as a sensor of PIP(2) density

21 January 2018

1 reference

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The polybasic region that follows the plant homeodomain zinc finger 1 of Pf1 is necessary and sufficient for specific phosphoinositide binding

21 January 2018

1 reference

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Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity

21 January 2018

1 reference

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PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane

21 January 2018

1 reference

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The phosphoinositide 3-kinase pathway

21 January 2018

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PIP2 and PIP3: complex roles at the cell surface

21 January 2018

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PIP(2) and proteins: interactions, organization, and information flow

21 January 2018

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The role of phosphoinositides in membrane transport

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M703537200

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17 September 2017

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