Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions (Q40097780)

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scientific article published on 27 July 2017

Language	Label	Description	Also known as
English	Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions	scientific article published on 27 July 2017

Statements

scholarly article

1 reference

Europe PubMed Central

17 September 2017

Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions (English)

1 reference

Europe PubMed Central

17 September 2017

protein-protein interaction

1 reference

based on heuristic

inferred from title

Brucella melitensis

object named as

Brucella melitensis

1 reference

based on heuristic

inferred from title

author name string

Carlos A Rossetti

1

1 reference

Europe PubMed Central

17 September 2017

Kenneth L Drake

2

1 reference

Europe PubMed Central

17 September 2017

Sara D Lawhon

3

1 reference

Europe PubMed Central

17 September 2017

Jairo S Nunes

4

1 reference

Europe PubMed Central

17 September 2017

Tamara Gull

5

1 reference

Europe PubMed Central

17 September 2017

Sangeeta Khare

6

1 reference

Europe PubMed Central

17 September 2017

Leslie G Adams

7

1 reference

Europe PubMed Central

17 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

27 July 2017

1 reference

Europe PubMed Central

17 September 2017

Frontiers in Microbiology

1 reference

Europe PubMed Central

17 September 2017

8

1 reference

Europe PubMed Central

17 September 2017

1275

1 reference

Europe PubMed Central

17 September 2017

RegA Plays a Key Role in Oxygen-Dependent Establishment of Persistence and in Isocitrate Lyase Activity, a Critical Determinant of In vivo Brucella suis Pathogenicity.

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A T4SS Effector Targets Host Cell Alpha-Enolase Contributing to Brucella abortus Intracellular Lifestyle

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KEGG: new perspectives on genomes, pathways, diseases and drugs

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Systems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections

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22 September 2017

Proteomic Profile of Brucella abortus-Infected Bovine Chorioallantoic Membrane Explants

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VirJ Is a Brucella Virulence Factor Involved in the Secretion of Type IV Secreted Substrates

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Type IV secretion system of Brucella spp. and its effectors

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Cervical Lymph Nodes as a Selective Niche for Brucella during Oral Infections

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Pathogenesis and immunobiology of brucellosis: review of Brucella-host interactions

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Detection of Brucella melitensis in bovine milk and milk products from apparently healthy animals in Egypt by real-time PCR.

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Brucella papionis sp. nov., isolated from baboons (Papio spp.).

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The invA gene of Brucella melitensis is involved in intracellular invasion and is required to establish infection in a mouse model

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The BtaF trimeric autotransporter of Brucella suis is involved in attachment to various surfaces, resistance to serum and virulence

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Microarray-based identification of differentially expressed genes in intracellular Brucella abortus within RAW264.7 cells

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BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions

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Global Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses.

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Sensing of bacterial type IV secretion via the unfolded protein response

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BtaE, an adhesin that belongs to the trimeric autotransporter family, is required for full virulence and defines a specific adhesive pole of Brucella suis

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Clinical manifestations of human brucellosis: a systematic review and meta-analysis

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Innate immune recognition of flagellin limits systemic persistence of Brucella

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Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells

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Complete genome sequence of Brucella melitensis biovar 3 strain NI, isolated from an aborted bovine fetus

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Analyses of Brucella pathogenesis, host immunity, and vaccine targets using systems biology and bioinformatics

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Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune tolerance

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The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes.

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Transcriptome analysis of HeLa cells response to Brucella melitensis infection: a molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis

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BmaC, a novel autotransporter of Brucella suis, is involved in bacterial adhesion to host cells

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Role of SPI-1 secreted effectors in acute bovine response to Salmonella enterica Serovar Typhimurium: a systems biology analysis approach

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Brucella genomics as we enter the multi-genome era.

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Transcriptional profile of the intracellular pathogen Brucella melitensis following HeLa cells infection

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22 September 2017

In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system

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Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2.

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Comparative analysis of the early transcriptome of Brucella abortus--infected monocyte-derived macrophages from cattle naturally resistant or susceptible to brucellosis

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Selective amplification of Brucella melitensis mRNA from a mixed host-pathogen total RNA.

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Gut inflammation provides a respiratory electron acceptor for Salmonella

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Insights into the problem of B. Melitensis and rationalizing a vaccination programme in Israel

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22 September 2017

Brucella melitensis VjbR and C12-HSL regulons: contributions of the N-dodecanoyl homoserine lactone signaling molecule and LuxR homologue VjbR to gene expression

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22 September 2017

Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system

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Disruption of the BMEI0066 gene attenuates the virulence of Brucella melitensis and decreases its stress tolerance

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'Guilty by Association' - Protein-Protein Interactions (PPIs) in Bacterial Pathogens.

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Brucella melitensis global gene expression study provides novel information on growth phase-specific gene regulation with potential insights for understanding Brucella:host initial interactions

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Comparative proteomics analyses reveal the virB of B. melitensis affects expression of intracellular survival related proteins

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Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system

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Quantitative analysis of the intramacrophagic Brucella suis proteome reveals metabolic adaptation to late stage of cellular infection

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VirB3 to VirB6 and VirB8 to VirB11, but not VirB7, are essential for mediating persistence of Brucella in the reticuloendothelial system

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Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella.

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Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1.

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Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection

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Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival

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FtcR is a new master regulator of the flagellar system of Brucella melitensis 16M with homologs in Rhizobiaceae.

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A B lymphocyte mitogen is a Brucella abortus virulence factor required for persistent infection

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Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages.

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Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development.

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Brucella abortus rough mutants induce macrophage oncosis that requires bacterial protein synthesis and direct interaction with the macrophage.

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22 September 2017

Brucella abortus synthesizes phosphatidylcholine from choline provided by the host

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22 September 2017

Effects of flagellin on innate and adaptive immunity

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22 September 2017

The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection

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22 September 2017

Integration host factor is involved in transcriptional regulation of the Brucella abortus virB operon.

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22 September 2017

Combining microarrays and biological knowledge for estimating gene networks via bayesian networks

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Different responses of macrophages to smooth and rough Brucella spp.: relationship to virulence

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Brucella abortus rough mutants are cytopathic for macrophages in culture

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Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum

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22 September 2017

Cellular prion protein promotes Brucella infection into macrophages

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22 September 2017

The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell

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22 September 2017

Brucella proteomes--a review

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The pathology of brucellosis reflects the outcome of the battle between the host genome and the Brucella genome

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22 September 2017

The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts

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22 September 2017

The two-component system BvrR/BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae

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22 September 2017

Global analysis of the Brucella melitensis proteome: Identification of proteins expressed in laboratory-grown culture

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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22 September 2017

The Brucella suis virB operon is induced intracellularly in macrophages

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22 September 2017

Brucella melitensis: a nasty bug with hidden credentials for virulence

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22 September 2017

Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks

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22 September 2017

Using Bayesian networks to analyze expression data

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22 September 2017

Identification and characterization of in vivo attenuated mutants of Brucella melitensis

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22 September 2017

A homologue of an operon required for DNA transfer in Agrobacterium is required in Brucella abortus for virulence and intracellular multiplication

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22 September 2017

Identification of Brucella suis genes affecting intracellular survival in an in vitro human macrophage infection model by signature-tagged transposon mutagenesis

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22 September 2017

Investigation into the role of the response regulator NtrC in the metabolism and virulence of Brucella suis.

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22 September 2017

Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival

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22 September 2017

The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides

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22 September 2017

BigA is a novel adhesin of Brucella that mediates adhesion to epithelial cells

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25 September 2017

A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

25 September 2017

Identification, cloning and initial characterisation of FeuPQ in Brucella suis: a new sub-family of two-component regulatory systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

25 September 2017

Morphologic and molecular characterization of Salmonella typhimurium infection in neonatal calves.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

15 June 2018

Interspecific transmission of Brucella abortus from experimentally infected coyotes (Canis latrans) to parturient cattle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

15 June 2018

Computational prediction of secretion systems and secretomes of Brucella: identification of novel type IV effectors and their interaction with the host.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

The effects of MucR on expression of type IV secretion system, quorum sensing system and stress responses in Brucella melitensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

The two-component system PrlS/PrlR of Brucella melitensis is required for persistence in mice and appears to respond to ionic strength.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Mice lacking components of adaptive immunity show increased Brucella abortus virB mutant colonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Characterization of SP41, a surface protein of Brucella associated with adherence and invasion of host epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Characterization of biological activities of Brucella melitensis lipopolysaccharide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Brucella lipopolysaccharide acts as a virulence factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529337

20 August 2018

Cyclic β-1,2-glucan is a brucella virulence factor required for intracellular survival

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Synthesis of phosphatidylcholine, a typical eukaryotic phospholipid, is necessary for full virulence of the intracellular bacterial parasite Brucella abortus

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Brucella abortus Lipopolysaccharide in Murine Peritoneal Macrophages Acts as a Down-Regulator of T Cell Activation

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Management of an outbreak of brucellosis due to B. melitensis in dairy cattle in Spain

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Early phase morphological lesions and transcriptional responses of bovine ileum infected with Mycobacterium avium subsp. paratuberculosis

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Differences in two-component signal transduction proteins among the genus Brucella: Implications for host preference and pathogenesis

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Cutting Edge: Brucella abortus Exploits a Cellular Prion Protein on Intestinal M Cells as an Invasive Receptor

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

RpoE1, an extracytoplasmic function sigma factor, is a repressor of the flagellar system in Brucella melitensis

1 reference

https://api.crossref.org/works/10.3389%2FFMICB.2017.01275

21 January 2018

Brucella melitensis infection discovered in cattle for first time, goats also infected

1 reference

https://pubmed.ncbi.nlm.nih.gov/28798726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FMICB.2017.01275

1 reference

Europe PubMed Central

17 September 2017

release_4juw3gv4gnb3dozzlh4lfxdsta

1 reference

https://api.fatcat.wiki/v0/release/4juw3gv4gnb3dozzlh4lfxdsta

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

17 September 2017

1 reference

Europe PubMed Central

17 September 2017

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