Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2. (Q40094179)

17 September 2017

Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2. (English)

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Human T-lymphotropic virus 1

17 September 2017

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Saurabh K Gupta

1

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17 September 2017

Xin Guo

2

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17 September 2017

Sarah S Durkin

3

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17 September 2017

Kimberly F Fryrear

4

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17 September 2017

Michael D Ward

5

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17 September 2017

O John Semmes

6

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17 September 2017

language of work or name

English

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publication date

13 August 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

29431-29440

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17 September 2017

40

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Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

17 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Discovery of adult T-cell leukemia

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Genomic stability and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Inactivation of hTERT transcription by Tax.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Clastogenic effect of the human T-cell leukemia virus type I Tax oncoprotein correlates with unstabilized DNA breaks

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Induction of micronuclei by HTLV-I Tax: a cellular assay for function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Trans-activator Tax of human T-cell leukemia virus type 1 enhances mutation frequency of the cellular genome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Impact of HTLV-I Tax on cell cycle progression and the cellular DNA damage repair response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

HTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Human T-lymphotropic virus type 1 oncoprotein tax promotes S-phase entry but blocks mitosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Adult T cell leukemia: a tale of two T cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Mutation analysis of the CHK2 gene in families with hereditary breast cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

Analysis of the CHK2 gene in lymphoid malignancies

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Chk2 activation and phosphorylation-dependent oligomerization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

DNA damage regulates Chk2 association with chromatin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

DNA damage-dependent cell cycle checkpoints and genomic stability

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Sensing, signaling, and responding to DNA damage: organization of the checkpoint pathways in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

DNA damage checkpoints in mammals

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

DNA damage-induced cohesion.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G2 arrest mediated by Chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

21 January 2018

The Chk2 protein kinase

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M704110200

HTLV-I Tax self-association in optimal trans-activation function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704110200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704110200

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17 September 2017

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