The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms (Q40088322)

17 September 2017

The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms (English)

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17 September 2017

5

Heike Münzberg

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17 September 2017

Yusong Gong

1

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17 September 2017

Ryoko Ishida-Takahashi

2

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17 September 2017

Eneida C Villanueva

3

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17 September 2017

Diane C Fingar

4

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17 September 2017

Martin G Myers

6

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17 September 2017

language of work or name

English

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publication date

28 August 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

42

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17 September 2017

31019-31027

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Prevalence of overweight and obesity in the United States, 1999-2004

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1 reference

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Lifetime Risk for Diabetes Mellitus in the United States

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Cellular warriors at the battle of the bulge

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Unraveling the central nervous system pathways underlying responses to leptin

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Monogenic human obesity syndromes.

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Leptin and the regulation of body weight in mammals

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Leptin receptor signaling and the regulation of mammalian physiology

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Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis

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Role of leptin in the neuroendocrine response to fasting

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1 reference

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Positional cloning of the mouse obese gene and its human homologue

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Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

21 January 2018

1 reference

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Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

1 reference

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Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene

21 January 2018

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

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21 January 2018

The many lives of leptin

1 reference

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Leptin receptor action and mechanisms of leptin resistance

21 January 2018

1 reference

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The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

1 reference

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Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

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Activation of downstream signals by the long form of the leptin receptor

21 January 2018

1 reference

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Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

1 reference

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

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Divergent roles of SHP-2 in ERK activation by leptin receptors

21 January 2018

1 reference

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SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

1 reference

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Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3.

21 January 2018

1 reference

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CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

21 January 2018

1 reference

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Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Defective STAT signaling by the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

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Hypothalamic mTOR signaling regulates food intake

21 January 2018

1 reference

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Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 January 2018

1 reference

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

21 January 2018

1 reference

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mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

21 January 2018

1 reference

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Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo

21 January 2018

1 reference

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Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling

21 January 2018

1 reference

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General nature of the STAT3-activated anti-inflammatory response.

21 January 2018

1 reference

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Regulation of Jak kinases by intracellular leptin receptor sequences.

21 January 2018

1 reference

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S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 January 2018

1 reference

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Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin receptor signaling and action in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

21 January 2018

1 reference

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

1 reference

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Functional roles of STAT family proteins: lessons from knockout mice

21 January 2018

1 reference

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A complex interaction pattern of CIS and SOCS2 with the leptin receptor

21 January 2018

1 reference

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Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

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LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin

21 January 2018

1 reference

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M702838200

1 reference

17 September 2017

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