MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA. (Q40082913)

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6 January 2020

title

MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA (English)

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6 January 2020

2

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6 January 2020

author name string

A Phillips

series ordinal

1

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language of work or name

English

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publication date

10 September 2007

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6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

27

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6 January 2020

issue

11

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page(s)

1645-1649

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210785

6 January 2020

exact match

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cites work

Mapping of the p53 and mdm-2 interaction domains

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Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

21 January 2018

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Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2.

21 January 2018

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7 January 2021

The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2.

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7 January 2021

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

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7 January 2021

A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans

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7 January 2021

p53 ubiquitination: Mdm2 and beyond

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7 January 2021

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

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7 January 2021

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR

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7 January 2021

eIF4E is a central node of an RNA regulon that governs cellular proliferation

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

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7 January 2021

Nuclear export of mRNA: from the site of transcription to the cytoplasm

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7 January 2021

Delineation of mRNA export pathways by the use of cell-permeable peptides

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7 January 2021

Organizing mRNA export

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7 January 2021

Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

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7 January 2021

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation

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7 January 2021

eIF4E--from translation to transformation

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

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7 January 2021

MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.

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7 January 2021

GC-selective DNA-binding antibiotic, mithramycin A, reveals multiple points of control in the regulation of Hdm2 protein synthesis.

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7 January 2021

The mechanisms of regulation of Hdm2 protein level by serum growth factors

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7 January 2021

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

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7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

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7 January 2021

Induction of Mdm2 and enhancement of cell survival by bFGF.

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7 January 2021

Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis

1 reference

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7 January 2021

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

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7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

The mRNA cap-binding protein eIF4E in post-transcriptional gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

Dual-site regulation of MDM2 E3-ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

A functional p53-responsive intronic promoter is contained within the human mdm2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

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