Differential effects of cetuximab and AEE 788 on epidermal growth factor receptor (EGF-R) and vascular endothelial growth factor receptor (VEGF-R) in thyroid cancer cell lines. (Q40079882)

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English	Differential effects of cetuximab and AEE 788 on epidermal growth factor receptor (EGF-R) and vascular endothelial growth factor receptor (VEGF-R) in thyroid cancer cell lines.	scientific article

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7 January 2020

Differential effects of cetuximab and AEE 788 on epidermal growth factor receptor (EGF-R) and vascular endothelial growth factor receptor (VEGF-R) in thyroid cancer cell lines (English)

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7 January 2020

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Lorenz C Hofbauer

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7 January 2020

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S Hoffmann

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7 January 2020

A Burchert

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A Wunderlich

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Y Wang

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S Lingelbach

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M Rothmund

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A Zielke

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7 January 2020

https://scigraph.springernature.com/pub.10.1007/s12020-007-0008-9

0 references

Prognostic impact of EGF-receptor in papillary thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS12020-007-0008-9

21 January 2018

Presence of aberrant transcripts of ret proto-oncogene in a human papillary thyroid carcinoma cell line

1 reference

https://api.crossref.org/works/10.1007%2FS12020-007-0008-9

21 January 2018

Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paneling human thyroid cancer cell lines for candidate proteins for targeted anti-angiogenic therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor in thyroid cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody therapy of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential responses by pancreatic carcinoma cell lines to prolonged exposure to Erbitux (IMC-C225) anti-EGFR antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor (VEGF) and its receptors in thyroid carcinomas of follicular origin: a potential autocrine loop.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor-C in benign and malignant thyroid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab and irinotecan interact synergistically to inhibit the growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor monoclonal antibody inhibits growth of anaplastic thyroid cancer xenografts in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor biology (IMC-C225).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a highly differentiated thyroid cancer cell line of Hürthle cell origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Well differentiated thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of vascular endothelial growth factor and epidermal growth factor in development of papillary thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p44/p42-MAP kinase expression in papillary thyroid carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaplastic thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo angiogenesis in PC12 pheochromocytoma cells is mediated by vascular endothelial growth factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrations of growth factor control in metastatic follicular thyroid cancer in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-angiogenic functions of VEGF in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt: a potential target for thyroid cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors in papillary thyroid cancer: an evaluation of 601 consecutive patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular biology of the human anaplastic thyroid carcinoma cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What Is the Evidence That Tumors Are Angiogenesis Dependent?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnostic and prognostic value of angiogenesis-modulating genes in malignant thyroid neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in the thyroid gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralizing vascular endothelial growth factor activity inhibits thyroid cancer growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaplastic thyroid carcinoma: a 50-year experience at a single institution

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenes and growth factors in thyroid carcinogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaplastic thyroid carcinoma: a therapeutic challenge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying differentially expressed genes associated with metastasis of follicular thyroid cancer by cDNA expression array.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Additive antitumor effects of gefitinib and imatinib on anaplastic thyroid cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin (TSH)-induced production of vascular endothelial growth factor in thyroid cancer cells in vitro: evaluation of TSH signal transduction and of angiogenesis-stimulating growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the mitogen-activated protein kinase cellular signaling pathway in tumor cell survival and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the human TSH receptor in a human thyroid carcinoma cell line that lacks an endogenous TSH receptor: growth inhibition by cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modern approaches to age-old questions about thyroid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary tumor-transforming gene regulates multiple downstream angiogenic genes in thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression and overactivation of Akt in thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic administration of vascular endothelial growth factor monoclonal antibody reduces the growth of papillary thyroid carcinoma in a nude mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor enhances proliferation, migration, and invasion of follicular and papillary thyroid cancer in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptors and adenylate cyclase activity in human thyroid tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition of human papillary thyroid carcinoma cells and multicellular spheroids by anti-EGF-receptor antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17873319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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