Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity (Q40078414)

17 September 2017

Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity (English)

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17 September 2017

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Lena Thyrell

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17 September 2017

Velmurugesan Arulampalam

2

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17 September 2017

Linn Hjortsberg

3

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17 September 2017

Marianne Farnebo

4

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17 September 2017

Dan Grandér

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17 September 2017

Katja Pokrovskaja Tamm

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17 September 2017

language of work or name

English

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publication date

16 August 2007

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Experimental Cell Research

17 September 2017

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17 September 2017

313

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17 September 2017

19

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17 September 2017

4015-4024

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Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry

17 September 2017

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interferons as antiangiogenic agents

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interleukin-6 sensitizes multiple myeloma cell lines for apoptosis induced by interferon-alpha

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Human myeloma cell apoptosis induced by interferon-alpha

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Mechanisms of Interferon-alpha induced apoptosis in malignant cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Alternative signaling pathways regulating type I interferon-induced apoptosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

How cells respond to interferons

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

The role of STATs in transcriptional control and their impact on cellular function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

PML mediates IFN-alpha-induced apoptosis in myeloma by regulating TRAIL induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interferon-alpha down-regulates the interleukin-6 receptor in a human multiple myeloma cell line, U266.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.08.007

10.1016/J.YEXCR.2007.08.007

7 January 2021

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DOI

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17 September 2017

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