Construction of SH-EP1-alpha4beta2-hAPP695 cell line and effects of nicotinic agonists on beta-amyloid in the cells (Q40072727)

17 September 2017

title

Construction of SH-EP1-alpha4beta2-hAPP695 cell line and effects of nicotinic agonists on beta-amyloid in the cells (English)

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17 September 2017

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Huizhen Nie

1

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17 September 2017

Zuoqing Li

2

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17 September 2017

Ronald J Lukas

3

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17 September 2017

Yinghua Shen

4

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17 September 2017

Li Song

5

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17 September 2017

Xin Wang

6

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17 September 2017

Ming Yin

7

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17 September 2017

publication date

3 October 2007

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Cellular and Molecular Neurobiology

17 September 2017

published in

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17 September 2017

volume

28

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17 September 2017

issue

1

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17 September 2017

page(s)

103-112

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https://scigraph.springernature.com/pub.10.1007/s10571-007-9218-1

17 September 2017

exact match

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cites work

Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.

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Crossref

https://api.crossref.org/works/10.1007%2FS10571-007-9218-1

Alzheimer's disease and the amyloid cascade hypothesis: ten years on.

21 January 2018

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12 December 2020

Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes

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Neuronal nicotinic receptors: from structure to pathology

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The cause of neuronal degeneration in Alzheimer's disease

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The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the path

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Correlations of synaptic and pathological markers with cognition of the elderly

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Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model

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Neuronal nicotinic receptors in the human brain

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12 December 2020

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

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12 December 2020

Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum.

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12 December 2020

Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production

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12 December 2020

Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography

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12 December 2020

Nicotinic acetylcholine receptors in Alzheimer's disease

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12 December 2020

Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

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12 December 2020

Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography

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12 December 2020

Ispronicline: a novel alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties

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12 December 2020

Effect of ispronicline, a neuronal nicotinic acetylcholine receptor partial agonist, in subjects with age associated memory impairment (AAMI)

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12 December 2020

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

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12 December 2020

Evidence of a functional alpha7-neuronal nicotinic receptor subtype located on motoneurons of the dorsal motor nucleus of the vagus

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12 December 2020

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

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12 December 2020

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

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12 December 2020

Brain neuronal nicotinic receptors as new targets for drug discovery

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Emerging structure of the nicotinic acetylcholine receptors

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12 December 2020

Pathways towards and away from Alzheimer's disease

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12 December 2020

The role of nicotinic acetylcholine receptors in Alzheimer's disease

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12 December 2020

Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice.

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12 December 2020

Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons.

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12 December 2020

Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain

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12 December 2020

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

12 December 2020

Amyloid beta-protein precursor: new clues to the genesis of Alzheimer's disease

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12 December 2020

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

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12 December 2020

Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice

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12 December 2020

10.1007/S10571-007-9218-1

Identifiers

DOI

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Dimensions Publication ID

17 September 2017

1019490644

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