PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis (Q40070753)

17 September 2017

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis (English)

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17 September 2017

E Davicioni

3

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author name string

F Graf Finckenstein

1

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17 September 2017

V Shahbazian

2

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17 September 2017

Y-X Ren

4

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17 September 2017

M J Anderson

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17 September 2017

language of work or name

English

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publication date

8 October 2007

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17 September 2017

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17 September 2017

27

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2004-2014

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17 September 2017

14

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210835

17 September 2017

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cites work

PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma

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Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

21 January 2018

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Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma

21 January 2018

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Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

21 January 2018

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The molecular basis of the undulated/Pax-1 mutation

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Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas

21 January 2018

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Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma

21 January 2018

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Expression of a single transfected cDNA converts fibroblasts to myoblasts

21 January 2018

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Pax3 inhibits myogenic differentiation of cultured myoblast cells

21 January 2018

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Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor

21 January 2018

1 reference

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The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

21 January 2018

1 reference

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Regulatory Elements that Control the Lineage-Specific Expression of myoD

21 January 2018

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Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

21 January 2018

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cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

21 January 2018

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The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

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Pax3 functions at a nodal point in melanocyte stem cell differentiation

21 January 2018

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FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains

21 January 2018

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Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

21 January 2018

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Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

21 January 2018

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pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation

21 January 2018

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Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications

21 January 2018

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A PANorama of PAX genes in cancer and development

21 January 2018

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A novel myoblast enhancer element mediates MyoD transcription

21 January 2018

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Identification of a new class of PAX3-FKHR target promoters: a role of the Pax3 paired box DNA binding domain

21 January 2018

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Cellular differentiation and prognosis in embryonal rhabdomyosarcoma. A report from the Cooperative Soft Tissue Sarcoma Study 1981 (CWS 81)

21 January 2018

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7 January 2021

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Identifiers

DOI

10.1038/SJ.ONC.1210835

1 reference

Dimensions Publication ID

17 September 2017

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1 reference